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Information Journal Paper

Title

Assessment of Maternal Vitamin D and CRP Plasma Levels Correlation to Preeclampsia and Its Severity: Case Control Study

Pages

  223-232

Abstract

 Introduction: Preeclampsia is a serious, inflammatory-mediated hypertensive disorder of Pregnancy affecting approximately 8% of all pregnancies. Based on recent studies, women with Vitamin D deficiency may have an increased risk of developing Preeclampsia. The aim of the study was to evaluate the Vitamin D and CRP levels and explore the role and correlation between each other and also occurrence of Preeclampsia. Material and methods: 55 preeclamptic women and 55 healthy pregnant women were selected from Kamali hospital in karaj, Iran. 6 ml of venous blood sample was collected from each pregnant woman and the serum 25-OH-D and CRP levels were measured by ELISA which reported in ng/mL and mg/dL, respectively. Data were analyzed by independent t-test, Mann-Whitney U test, Chi square and logistic regression. Results: Preeclamptic women (n=55) were noted to have decreased total 25-OH-D and elevated CRP levels relative to healthy control women (n=55; P<0. 001). This difference in Vitamin D deficiency remained significant after adjustment for maternal age and BMI [odds ratio (OR) = 12. 54, confidence interval (CI) = 1. 03– 154. 95, P=0. 047]. Conclusion: These results showed that Vitamin D deficiency and abnormal inflammatory status have a statistically significant relationship with Preeclampsia and support the hypothesis that Vitamin D deficiency may be a risk factor for Preeclampsia in the context of an inflammatory condition.

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    APA: Copy

    BADEHNOOSH, BITA, TAJBAKHSH, RAMIN, KABIR, KOUROSH, & Azadi, Kiarash. (2021). Assessment of Maternal Vitamin D and CRP Plasma Levels Correlation to Preeclampsia and Its Severity: Case Control Study. ALBORZ UNIVERSITY MEDICAL JOURNAL, 10(2 ), 223-232. SID. https://sid.ir/paper/415398/en

    Vancouver: Copy

    BADEHNOOSH BITA, TAJBAKHSH RAMIN, KABIR KOUROSH, Azadi Kiarash. Assessment of Maternal Vitamin D and CRP Plasma Levels Correlation to Preeclampsia and Its Severity: Case Control Study. ALBORZ UNIVERSITY MEDICAL JOURNAL[Internet]. 2021;10(2 ):223-232. Available from: https://sid.ir/paper/415398/en

    IEEE: Copy

    BITA BADEHNOOSH, RAMIN TAJBAKHSH, KOUROSH KABIR, and Kiarash Azadi, “Assessment of Maternal Vitamin D and CRP Plasma Levels Correlation to Preeclampsia and Its Severity: Case Control Study,” ALBORZ UNIVERSITY MEDICAL JOURNAL, vol. 10, no. 2 , pp. 223–232, 2021, [Online]. Available: https://sid.ir/paper/415398/en

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