Effects of probiotic and alpha-lipoic acid supplements, separately or in combination on appetite in overweight individuals: A double blind randomized clinical trial

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Nasiri Gholamreza; BASTANI ALI; HAJIAGHAMOHAMMADI ALI AKBAR; RASHIDI NOOSHABADI MOHAMADREZA; Shahmirzalou Parviz; KHADEM HAGHIGHIAN HOSSEIN

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Journal: Scientific Journal of Kurdistan University of Medical Sciences Year:2020 | Volume:25 | Issue:4 (108) Page(s): 1-19

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Title

Effects of probiotic and alpha-lipoic acid supplements, separately or in combination on appetite in overweight individuals: A double blind randomized clinical trial

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Keywords

ProbioticQ2

Alpha lipoic acidQ1

AppetiteQ1

OverweightQ2

Abstract

Background and Aim: The purpose of this study was to evaluate the effects of Probiotic and alpha-lipoic acid (ALA) supplements, on Appetite in Overweight people. Materials and Methods: This study included two phases of weight loss (8 weeks) and weight maintenance (16 weeks). Eighty-eight Overweight people were randomly divided into 4 groups: Isocaloric diet with Probiotic (500mg), isocaloric diet with ALA (600mg) and Probiotic, isocaloric diet with ALA and isocaloric diet with placebo groups. In the second phase, the participants received normal diet with the above-mentioned supplements. At the beginning and end of the first phase and at the end of the second phase, weight, body mass index (BMI), waist circumference (WC), hip circumference (HC), body fat percentage, Creactive protein (CRP), and Appetite were evalauted. We used SPSS software for statistical analysis. Independent sample t-test and ANOVA were used to compare the alterations in the mean values among the groups. Results: At the end of the first phase, the level of anthropometric changes, inflammatory factor and Appetite were significant in the intervention groups, but these changes were higher in the Probiotic + ALA group than in the other groups (P <0. 05). At the end of the second phase we found significant changes only in the Probiotic + ALA group (P<0. 05). Conclusion: Addition of Probiotic and ALA supplements to the normal diet can be effective in Appetite and weight management and also maintainance of weight loss which may be due to decreased inflammation.

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APA: Copy

Nasiri, Gholamreza, BASTANI, ALI, HAJIAGHAMOHAMMADI, ALI AKBAR, RASHIDI NOOSHABADI, MOHAMADREZA, Shahmirzalou, Parviz, & KHADEM HAGHIGHIAN, HOSSEIN. (2020). Effects of probiotic and alpha-lipoic acid supplements, separately or in combination on appetite in overweight individuals: A double blind randomized clinical trial. SCIENTIFIC JOURNAL OF KURDISTAN UNIVERSITY OF MEDICAL SCIENCES, 25(4 (108) ), 1-19. SID. https://sid.ir/paper/415870/en

Vancouver: Copy

Nasiri Gholamreza, BASTANI ALI, HAJIAGHAMOHAMMADI ALI AKBAR, RASHIDI NOOSHABADI MOHAMADREZA, Shahmirzalou Parviz, KHADEM HAGHIGHIAN HOSSEIN. Effects of probiotic and alpha-lipoic acid supplements, separately or in combination on appetite in overweight individuals: A double blind randomized clinical trial. SCIENTIFIC JOURNAL OF KURDISTAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2020;25(4 (108) ):1-19. Available from: https://sid.ir/paper/415870/en

IEEE: Copy

Gholamreza Nasiri, ALI BASTANI, ALI AKBAR HAJIAGHAMOHAMMADI, MOHAMADREZA RASHIDI NOOSHABADI, Parviz Shahmirzalou, and HOSSEIN KHADEM HAGHIGHIAN, “Effects of probiotic and alpha-lipoic acid supplements, separately or in combination on appetite in overweight individuals: A double blind randomized clinical trial,” SCIENTIFIC JOURNAL OF KURDISTAN UNIVERSITY OF MEDICAL SCIENCES, vol. 25, no. 4 (108) , pp. 1–19, 2020, [Online]. Available: https://sid.ir/paper/415870/en

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