PROTHROMBIN TIME AND ITS REPORTING PROCEDURE

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HABIBZADEH FAROKH; YAD ELAH M.; ROSHANI POUR M.; HAGHSHENAS M.

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Journal: Research in Medicine Year:2003 | Volume:26 | Issue:4 Page(s): 305-308

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Information Journal Paper

Title

PROTHROMBIN TIME AND ITS REPORTING PROCEDURE

Author(s)

HABIBZADEH FAROKH | YAD ELAH M. | ROSHANI POUR M. | HAGHSHENAS M. | Issue Writer Certificate

Keywords

ANTICOAGULANTSQ3

PTQ4

Abstract

In several conditions such as deep venous thrombosis, cerebral thrombosis, and valvular heart disease use of ANTICOAGULANTS (eg, warfarin) is mandatory. Since most of the clotting factors depressed by oral ANTICOAGULANTS are in the injury (extrinsic) pathway, the prothrombin time (PT) is the test of choice in controlling oral anticoagulant therapy. The PT results, however, show a significant interlaboratory variability. To harmonize the PT reports, a system that so called International Normalized Ratio (INR) was proposed. Using the INR, the interlaboratory variance should vanish and patients can be free to travel about without having any trouble with under- or over-anticoagulation. The current recommended INR ranges are 2.5-3.5 for patients with prosthetic mechanical heart valves, and those with myocardial infarction in whom oral anticoagulant therapy should be started. The recommended INR range for all other cases is 2-3. The INR should be the only reporting method for controlling oral anticoagulant dose adjustment.

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APA: Copy

HABIBZADEH, FAROKH, YAD ELAH, M., ROSHANI POUR, M., & HAGHSHENAS, M.. (2003). PROTHROMBIN TIME AND ITS REPORTING PROCEDURE. PAJOUHESH DAR PEZESHKI, 26(4), 305-308. SID. https://sid.ir/paper/41635/en

Vancouver: Copy

HABIBZADEH FAROKH, YAD ELAH M., ROSHANI POUR M., HAGHSHENAS M.. PROTHROMBIN TIME AND ITS REPORTING PROCEDURE. PAJOUHESH DAR PEZESHKI[Internet]. 2003;26(4):305-308. Available from: https://sid.ir/paper/41635/en

IEEE: Copy

FAROKH HABIBZADEH, M. YAD ELAH, M. ROSHANI POUR, and M. HAGHSHENAS, “PROTHROMBIN TIME AND ITS REPORTING PROCEDURE,” PAJOUHESH DAR PEZESHKI, vol. 26, no. 4, pp. 305–308, 2003, [Online]. Available: https://sid.ir/paper/41635/en

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