Effect of Endurance Training and Adenosine Injection on CCL2 Expression in Brain Ischemia-Reperfusion in Male Rats

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

Dehafarin Mohmad; Nameni Farah

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: SCIENTIFIC JOURNAL OF KURDISTAN UNIVERSITY OF MEDICAL SCIENCES Year:2021 | Volume:26 | Issue:4 (114) Page(s): 17-29

Download Full-Text

Persian Verion

View:

166

Download:

Cites:

Information Journal Paper

Title

Effect of Endurance Training and Adenosine Injection on CCL2 Expression in Brain Ischemia-Reperfusion in Male Rats

Author(s)

Dehafarin Mohmad | Nameni Farah | Issue Writer Certificate

Keywords

Regular exerciseQ2

Brain tissueQ1

StrokeQ1

NucleosideQ1

Abstract

Background and Aim: Regular exercise and proper exercise programs contribute to improvement of physiological function and improve aerobic capacity, blood absorption, and adequate oxygen supply for the brain and muscles. The aim of this study was to evaluate the effect of endurance training and adenosine injection on CCL2 gene expression after induction of cerebral ischemia reperfusion injury in male rats. Materials and Methods: This was an experimental study with a post-test design. The study population included Wistar rats. The sample consisted of 40 male rats which, after induction of ischemia, were randomly divided into the following groups: endurance training + adenosine + ischemia, ischemia + adenosine, endurance training + ischemia, and control + ischemia. After induction of ischemia, the animals performed an endurance training program. In the eighth week the rats received daily injection of 1 mg of adenosine. Then, CCL2 gene expression was measured using laboratory methods. We used mean, standard deviation, Shapiro-Wilks test, Leven test, and one-way analysis of variance (P ≤ 0. 05( for data analysis. Results: The results showed a significant difference between the control + ischemia group and the adenosine + ischemia group in the expression of the CCL2 gene. Also there was a significant difference between the control group + ischemia and the endurance training + ischemia group in the expression of the CCL2 gene. But we found no significant difference between the control group + ischemia and the endurance training group + adenosine + ischemia group in the expression of CCL2 gene. Conclusion: Pretreatment with endurance training and adenosine before an ischemic Stroke might have regulated CCL2 gene expression. Exercise and adenosine may be useful prophylactic factors for ischemic Stroke.

Cites

No record.

References

No record.

Cite

APA: Copy

Dehafarin, Mohmad, & Nameni, Farah. (2021). Effect of Endurance Training and Adenosine Injection on CCL2 Expression in Brain Ischemia-Reperfusion in Male Rats. SCIENTIFIC JOURNAL OF KURDISTAN UNIVERSITY OF MEDICAL SCIENCES, 26(4 (114) ), 17-29. SID. https://sid.ir/paper/416433/en

Vancouver: Copy

Dehafarin Mohmad, Nameni Farah. Effect of Endurance Training and Adenosine Injection on CCL2 Expression in Brain Ischemia-Reperfusion in Male Rats. SCIENTIFIC JOURNAL OF KURDISTAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2021;26(4 (114) ):17-29. Available from: https://sid.ir/paper/416433/en

IEEE: Copy

Mohmad Dehafarin, and Farah Nameni, “Effect of Endurance Training and Adenosine Injection on CCL2 Expression in Brain Ischemia-Reperfusion in Male Rats,” SCIENTIFIC JOURNAL OF KURDISTAN UNIVERSITY OF MEDICAL SCIENCES, vol. 26, no. 4 (114) , pp. 17–29, 2021, [Online]. Available: https://sid.ir/paper/416433/en

Related Journal Papers

No record.

Related Seminar Papers

No record.

Related Plans

No record.

Recommended Workshops