Leukocytes Parameters, CRP, and Ferritin in Iranian Patients with COVID-19 Infection; A Cross-sectional Study

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Karpians Gevik; PIRANFAR VAHHAB; Yahyavi Isar; Sepanian Teni; Sepanian Tadeh; ALIZADEH SAMANEH; Chandhal Arefeh

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Journal: IRANIAN JOURNAL OF MEDICAL MICROBIOLOGY Year:2021 | Volume:15 | Issue:3 Page(s): 360-367

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Title

Leukocytes Parameters, CRP, and Ferritin in Iranian Patients with COVID-19 Infection; A Cross-sectional Study

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Keywords

Acute respiratory distress syndromeQ1

CoronavirusQ1

Cytokine release syndromeQ1

LymphopeniaQ1

Real Time PCRQ1

Severe acute respiratory syndromeQ1

Abstract

Background and Aim: Coronavirus disease known as COVID-19 pandemic is caused by Severe acute respiratory syndrome Coronavirus 2 (SARS-CoV-2), which is affecting over 200 countries all over the world. This study was aimed to identify simple and swiftly available laboratory biomarkers to help facilitate effectual triage to categorize suspected COVID-19 patients. Materials and Methods: According to a standard protocol, we collected clinical, etiological, and laboratory data of 140 patients who underwent diagnostic tests at Medical Laboratory Group, Tehran, Iran, from October 1 to November 28, 2020, based on PCR testing for SARS-CoV-2 infection. Leukocyte parameters, C-reactive protein (CRP) and, ferritin levels were measured in patients with positive PCR COVID-19 test. Results: 140 patients with COVID-19 infection were included in the study. The median age in women was 41. 5 (23-60) years and 45. 3 (22-68) years in men. Based on RT-PCR result, there were significant differences for neutrophil, lymphocyte, and monocyte counts. Overall, 72. 8% of patients had monocyte count more than 11 ×109 /L. The mean neutrophil lymphocyte ratio (NLR) for women was 2. 8 (SD: 1. 8) and 2. 6 (SD: 1. 7) for men. Only in 15 patients (10. 7%) with respiratory symptoms, CRP level was more than 5 mg/L. Conclusion: We found a significant increase in monocyte count. Lymphopenia was also observed. In patients with respiratory symptoms, CRP was significantly higher than the normal reference range.

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APA: Copy

Karpians, Gevik, PIRANFAR, VAHHAB, Yahyavi, Isar, Sepanian, Teni, Sepanian, Tadeh, ALIZADEH, SAMANEH, & Chandhal, Arefeh. (2021). Leukocytes Parameters, CRP, and Ferritin in Iranian Patients with COVID-19 Infection; A Cross-sectional Study. IRANIAN JOURNAL OF MEDICAL MICROBIOLOGY, 15(3 ), 360-367. SID. https://sid.ir/paper/416449/en

Vancouver: Copy

Karpians Gevik, PIRANFAR VAHHAB, Yahyavi Isar, Sepanian Teni, Sepanian Tadeh, ALIZADEH SAMANEH, Chandhal Arefeh. Leukocytes Parameters, CRP, and Ferritin in Iranian Patients with COVID-19 Infection; A Cross-sectional Study. IRANIAN JOURNAL OF MEDICAL MICROBIOLOGY[Internet]. 2021;15(3 ):360-367. Available from: https://sid.ir/paper/416449/en

IEEE: Copy

Gevik Karpians, VAHHAB PIRANFAR, Isar Yahyavi, Teni Sepanian, Tadeh Sepanian, SAMANEH ALIZADEH, and Arefeh Chandhal, “Leukocytes Parameters, CRP, and Ferritin in Iranian Patients with COVID-19 Infection; A Cross-sectional Study,” IRANIAN JOURNAL OF MEDICAL MICROBIOLOGY, vol. 15, no. 3 , pp. 360–367, 2021, [Online]. Available: https://sid.ir/paper/416449/en

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