CYCLOOXYGENASE; PREVENTION AND TREATMENT

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SHARIFI R.; HEDAYATI MAHDI; RASMI Y.; RAHMATI YAMCHI M.; FATEMI F.; DADKHAH A.; ALAMEH A.A.A.

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Journal: Research in Medicine Year:2007 | Volume:31 | Issue:3 Page(s): 289-297

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Information Journal Paper

Title

CYCLOOXYGENASE; PREVENTION AND TREATMENT

Author(s)

Keywords

CYCLOOXYGENASEQ3

CANCERQ2

PROSTAGLANDINQ3

NON-STEROIDAL ANTI-INFLAMMATORY DRUGSQ3

Abstract

CYCLOOXYGENASE (COX) is the key enzyme required for the conversion of arachidonic acid to PROSTAGLANDINs. Two cycloxygenase isoforms have been identified and are referred to as COX-I and COX-2. Both enzymes are blocked by nonselective anti-inflammatory drugs (NSAID), such as indomethacin and ibuprofen. COX-I is an enzyme normally found in tissues and is involved in physiological functions, while COX-2 is an acute phase reactant associated with inflammation. Recently, COX-2 has been found to be associated with hyperalgesia, angiogenesis, CANCER and Alzheimers disease. The suggestion that COX-2 is causally linked to CANCER offers a new approach to extending our knowledge about the neoplastic phenomenon and improving management of human malignant diseases.

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APA: Copy

SHARIFI, R., HEDAYATI, MAHDI, RASMI, Y., RAHMATI YAMCHI, M., FATEMI, F., DADKHAH, A., & ALAMEH, A.A.A.. (2007). CYCLOOXYGENASE; PREVENTION AND TREATMENT. PAJOUHESH DAR PEZESHKI, 31(3), 289-297. SID. https://sid.ir/paper/41756/en

Vancouver: Copy

SHARIFI R., HEDAYATI MAHDI, RASMI Y., RAHMATI YAMCHI M., FATEMI F., DADKHAH A., ALAMEH A.A.A.. CYCLOOXYGENASE; PREVENTION AND TREATMENT. PAJOUHESH DAR PEZESHKI[Internet]. 2007;31(3):289-297. Available from: https://sid.ir/paper/41756/en

IEEE: Copy

R. SHARIFI, MAHDI HEDAYATI, Y. RASMI, M. RAHMATI YAMCHI, F. FATEMI, A. DADKHAH, and A.A.A. ALAMEH, “CYCLOOXYGENASE; PREVENTION AND TREATMENT,” PAJOUHESH DAR PEZESHKI, vol. 31, no. 3, pp. 289–297, 2007, [Online]. Available: https://sid.ir/paper/41756/en

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