CHLAMYDIAL ANTIBODIES BY ELISA IN TUBAL FACTOR INFERTILITY

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GACHKAR L.; ESFANDIARI N.; HAMZEIE K.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Journal: Research in Medicine Year:2002 | Volume:26 | Issue:3 Page(s): 199-203

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Information Journal Paper

Title

CHLAMYDIAL ANTIBODIES BY ELISA IN TUBAL FACTOR INFERTILITY

Author(s)

GACHKAR L. | ESFANDIARI N. | HAMZEIE K. | Issue Writer Certificate

Keywords

CHLAMYDIA TRACHOMATISQ4

TUBAL FACTOR INFERTILITYQ4

CHLAMYDIAL ANTIBODIESQ4

ELISAQ2

Abstract

Background: Tubal factors. caused by infectious agents like CHLAMYDIA TRACHOMATIS. are among the most common cause of infertility. Laparascopic diagnosis of TUBAL FACTOR INFERTILITY is by far the most accurate. the most expensive and the most invasive technique.Hysterosalpingogarphy is accompanied by false positive and false negative results. During the past decade. measuring the CHLAMYDIAL ANTIBODIES by ELlSA is considered as an accurate.cheap and non invasive technique in the diagnosis of TUBAL FACTOR INFERTILITY. Thus. we have attempted to determine the efficacy of this technique.Materials and methods: It was a clinical trial. 65 infertile women referring to Sarem Medical Center were chosen by a nonprabability purposed sampling and undergone laparascopic procedure. Meanwhile, their hysterosalpingogarphic were reevaluated by a radiologist. CHLAMYDIAL ANTIBODIES (lgA. IgG. IgM) were measured using ELlSA technique. Results: Results have indicated that in the cut ot T point of 100 U/ml and with respect to the laparacopic findings the sensitivity. specificity. PPV. NPV and accuracy of IgM was 9%, 80%. 33%. 43%. and 41%, respectively. These figures were 31%. 67%,.52%.45%, and 48% fur IgG. At the cut off point of 200 U/ml the sensitivity. speciticity, PPV. NPV and accuracy of IgG were 23%. 93%. 80%. 51%, and 55%, respectively. With respect to the hysterosalpingogarphic findings these indices for IgM at the eut oil point of 100 U/ml were 15%. 84%. 25%. 74%. and 67%,respectively, however. they have calculated 46%, 74%, 38%, 80%. 67%. for IgG. At the cut off point of 200 U/ml the sensitivity, specificity, PPV, NPV and accuracy of IgG were 23%.84%,33%.76%, and 60%. respectively. None of the candidates have shown positive level of IgA.Conclusion: Results have revealed that at the cut off point of 100U/mL IgG and (gM have had a poor sensitivity. PPV. and accuracy when compared to laparascopy, but a satisfactory specificity was noted. Increasing the cut off point to 200U/ml was accompanied by better specificity and PPV, but still poor sensitivity and accuracy. At the cut off point of 100U/ml and with respect to the hysterosalpingogarphic findings. IgG and IgM had satisfactory specificity and IgM had satisfactory NPV, too. There was no significant difference as the cut off point was increased to 200U/ml.

Cites

A REVIEW OF THE ROLE OF MYCOPLASMA INFECTIONS IN HUMANS INFERTILITY

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APA: Copy

GACHKAR, L., ESFANDIARI, N., & HAMZEIE, K.. (2002). CHLAMYDIAL ANTIBODIES BY ELISA IN TUBAL FACTOR INFERTILITY. PAJOUHESH DAR PEZESHKI, 26(3), 199-203. SID. https://sid.ir/paper/42088/en

Vancouver: Copy

GACHKAR L., ESFANDIARI N., HAMZEIE K.. CHLAMYDIAL ANTIBODIES BY ELISA IN TUBAL FACTOR INFERTILITY. PAJOUHESH DAR PEZESHKI[Internet]. 2002;26(3):199-203. Available from: https://sid.ir/paper/42088/en

IEEE: Copy

L. GACHKAR, N. ESFANDIARI, and K. HAMZEIE, “CHLAMYDIAL ANTIBODIES BY ELISA IN TUBAL FACTOR INFERTILITY,” PAJOUHESH DAR PEZESHKI, vol. 26, no. 3, pp. 199–203, 2002, [Online]. Available: https://sid.ir/paper/42088/en

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