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Information Journal Paper

Title

SURVEYING TNF-ALFA CONCENTRATION IN CHRONIC HEPATITIS C PATIENTS AND ITS ASSOCIATION WITH HEPATIC FIBROSIS

Pages

  305-309

Abstract

 Background: TNF gene polymorphisms may influence hepatitis e virus activity. In the present study we surveyed TNF-a concentration in chronic hepatitis e patients and its association with hepatic FIBROSIS. Materials and methods: We investigated the association between TNF-a level and INFLAMMATORY NECROSIS/fibrosis grading, meanwhile, TNF association was investigated with anthropometric indices (body mass index, waist to hip ratio, waist circumference, sex, age), biochemical indices (triglyceride, cholesterol, fasting blood sugar, HOMA-IR, AST, ALT, insulin, peptide-c, INR) and also pathological findings.Results: The study population included 50 males and 10 females with the mean age of 34.9±1.0.6 years. the mean TNF level was 31.13±30 pg/ml.TNF was not associated with the following indices: age, sex, height, BMI, WHR, waist circumference, TG, cholesterol, FBS, HOMA-IR, insulin, peptide-c, INR, ferittin, transferrin, serum iron, steatosis and iron precipitate. However, TNF level was associated with drug abuse and alcohol (p<0.008, p<0.017). Based on logistic regression analysis, FBS, TG, iron level, peptide-c, height, total and indirect bilirubin were associated with TNF. Conclusion: TNF-a level was associated with FBS, TG, serum iron, peptide-c, total and indirect bilirubin, height, drug abuse, and alcohol use, however, it was not associated with INFLAMMATORY NECROSIS/fibrosis grading.

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    APA: Copy

    MOHAMMADALIZADEH, A.H., FALAHIAN, F., ALAVIAN, S.M., RAHIMI, FARZANEH, HEDAYATI, MAHDI, EYNI, E., ZALI, MOHAMMAD REZA, & AZIZI, FEREYDOUN. (2008). SURVEYING TNF-ALFA CONCENTRATION IN CHRONIC HEPATITIS C PATIENTS AND ITS ASSOCIATION WITH HEPATIC FIBROSIS. PAJOUHESH DAR PEZESHKI, 31(4), 305-309. SID. https://sid.ir/paper/42141/en

    Vancouver: Copy

    MOHAMMADALIZADEH A.H., FALAHIAN F., ALAVIAN S.M., RAHIMI FARZANEH, HEDAYATI MAHDI, EYNI E., ZALI MOHAMMAD REZA, AZIZI FEREYDOUN. SURVEYING TNF-ALFA CONCENTRATION IN CHRONIC HEPATITIS C PATIENTS AND ITS ASSOCIATION WITH HEPATIC FIBROSIS. PAJOUHESH DAR PEZESHKI[Internet]. 2008;31(4):305-309. Available from: https://sid.ir/paper/42141/en

    IEEE: Copy

    A.H. MOHAMMADALIZADEH, F. FALAHIAN, S.M. ALAVIAN, FARZANEH RAHIMI, MAHDI HEDAYATI, E. EYNI, MOHAMMAD REZA ZALI, and FEREYDOUN AZIZI, “SURVEYING TNF-ALFA CONCENTRATION IN CHRONIC HEPATITIS C PATIENTS AND ITS ASSOCIATION WITH HEPATIC FIBROSIS,” PAJOUHESH DAR PEZESHKI, vol. 31, no. 4, pp. 305–309, 2008, [Online]. Available: https://sid.ir/paper/42141/en

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