THE EFFECT OF AEROBIC TRAINING ON KLOTHO PROTEIN AND A SELECTED OF INFLAMMATORY INDICES IN KIDNEY OF MALE RATS

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MOEIN AKBAR; NIKBAKHT HOJATOLLAH; GHAZALIAN FARSHAD

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Journal: Research in Medicine Year:2017 | Volume:41 | Issue:3 Page(s): 175-182

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Information Journal Paper

Title

THE EFFECT OF AEROBIC TRAINING ON KLOTHO PROTEIN AND A SELECTED OF INFLAMMATORY INDICES IN KIDNEY OF MALE RATS

Author(s)

MOEIN AKBAR | NIKBAKHT HOJATOLLAH | GHAZALIAN FARSHAD | Issue Writer Certificate

Keywords

AEROBIC TRAININGQ1

KLOTHOQ1

TNF-αQ2

IL6Q1

Abstract

Backgrond: Considering the importance of the KLOTHO gene and cytokine proteins and the existence of some research on the effect of exercise on these proteins, the present study was carried out to examine the effect of AEROBIC TRAINING on KLOTHO protein, interleukin-6 and tumor necrosis factor alpha inflammatory factors in rats.Materials and Methods: For this purpose 12 male rats with an average weight 170g±5g and the age of eight weeks were divided into two groups: control (N=6) and experimental (N=6) groups. The experimental groups trained on a treadmill for 8 weeks and 3 sessions per week. 48 h after the last training session, both groups of rats were slaughtered ethically and kidney tissue was extracted. KLOTHO, IL-6 and TNF-a proteins of kidney tissues were measured and counted using by the western blot method.Findings: The KLOTHO protein (P=0.05) significantly increased in training rats compared with the control group. Also the IL-6 protein (P=0.05) significantly decreased in training rats compared with the control group. While the TNF-a protein (P=0.42) did not show a significant difference.Conclusion: AEROBIC TRAINING might increase the KLOTHO protein, on the other hand can also decrease the levels of IL-6 protein secreted by the kidney. So it can be said that probably AEROBIC TRAINING may delay aging symptoms and may decrease in inflammatory responses.

Cites

The Effect of Resistance Training Intervention on Serum Levels of some Anti-Aging and Rejuvenating Proteins in Older Men

References

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APA: Copy

MOEIN, AKBAR, NIKBAKHT, HOJATOLLAH, & GHAZALIAN, FARSHAD. (2017). THE EFFECT OF AEROBIC TRAINING ON KLOTHO PROTEIN AND A SELECTED OF INFLAMMATORY INDICES IN KIDNEY OF MALE RATS. PAJOUHESH DAR PEZESHKI, 41(3 ), 175-182. SID. https://sid.ir/paper/42203/en

Vancouver: Copy

MOEIN AKBAR, NIKBAKHT HOJATOLLAH, GHAZALIAN FARSHAD. THE EFFECT OF AEROBIC TRAINING ON KLOTHO PROTEIN AND A SELECTED OF INFLAMMATORY INDICES IN KIDNEY OF MALE RATS. PAJOUHESH DAR PEZESHKI[Internet]. 2017;41(3 ):175-182. Available from: https://sid.ir/paper/42203/en

IEEE: Copy

AKBAR MOEIN, HOJATOLLAH NIKBAKHT, and FARSHAD GHAZALIAN, “THE EFFECT OF AEROBIC TRAINING ON KLOTHO PROTEIN AND A SELECTED OF INFLAMMATORY INDICES IN KIDNEY OF MALE RATS,” PAJOUHESH DAR PEZESHKI, vol. 41, no. 3 , pp. 175–182, 2017, [Online]. Available: https://sid.ir/paper/42203/en

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