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مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Title

INJECTION OF MITOMYCIN-C IN NASOLACRIMAL DUCT FOR TREATMENT OF PARTIAL NASOLACRIMAL DUCT OBSTRUCTION

Pages

  221-225

Abstract

 Purpose: To determine the safety and efficacy of MITOMYCIN-C injection into the lacrimal duct for treatment of partial NASOLACRIMAL DUCT OBSTRUCTION in adults. Method: This is a before-after clinical trial performed on 20 patients with partial primary acquired NASOLACRIMAL DUCT OBSTRUCTION. We injected 1.5 ml of MITOMYCIN-C 0.2 mg/ml into the lacrimal duct and repeated it with concentration of 0.3 mg/ml for inadequate response.Results: After 9 months of follow up, epiphora decreased in 80% of the patients, while the amount of obstruction decreased to 50% In patients with low grade anatomical obstruction the improvement was 100% and with increasing degrees of obstruction, the success rate of this intervention decreased. Ophthalmic complications did not occur and nasal mucosal pallor was observed only in one patient. Conclusion: Intraductal mitomycin injection can reduce epiphora in adults with partial primary acquired NASOLACRIMAL DUCT OBSTRUCTION and is a safe method.

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    APA: Copy

    ZANJANI, H.A., HASHEMI, N., & HESHMATIPOUR, B.. (2005). INJECTION OF MITOMYCIN-C IN NASOLACRIMAL DUCT FOR TREATMENT OF PARTIAL NASOLACRIMAL DUCT OBSTRUCTION. BINA, 10(2 (38)), 221-225. SID. https://sid.ir/paper/42249/en

    Vancouver: Copy

    ZANJANI H.A., HASHEMI N., HESHMATIPOUR B.. INJECTION OF MITOMYCIN-C IN NASOLACRIMAL DUCT FOR TREATMENT OF PARTIAL NASOLACRIMAL DUCT OBSTRUCTION. BINA[Internet]. 2005;10(2 (38)):221-225. Available from: https://sid.ir/paper/42249/en

    IEEE: Copy

    H.A. ZANJANI, N. HASHEMI, and B. HESHMATIPOUR, “INJECTION OF MITOMYCIN-C IN NASOLACRIMAL DUCT FOR TREATMENT OF PARTIAL NASOLACRIMAL DUCT OBSTRUCTION,” BINA, vol. 10, no. 2 (38), pp. 221–225, 2005, [Online]. Available: https://sid.ir/paper/42249/en

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