TOPICAL 5-FLUOROURACIL FOR TREATMENT OF CONJUNCTIVAL OR CORNEAL INTRAEPITHELIAL NEOPLASIA

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ZAMANI M.; SHARIFIPOUR FARIDEH

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Paper Information

Journal: BINA Year:2004 | Volume:9 | Issue:4 (36) Page(s): 333-336

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Information Journal Paper

Title

TOPICAL 5-FLUOROURACIL FOR TREATMENT OF CONJUNCTIVAL OR CORNEAL INTRAEPITHELIAL NEOPLASIA

Author(s)

ZAMANI M. | SHARIFIPOUR FARIDEH | Issue Writer Certificate

Keywords

TOPICALQ3

5-FLUOROURACIL (5-FU)Q3

INTRAEPITHELIAL NEOPLASIAQ3

CONJUNCTIVAQ3

CORNEAQ3

Abstract

Purpose: To evaluate the efficacy of TOPICAL 5-Fluorouracil (5-FU) in the treatment of CONJUNCTIVAl and CORNEAl INTRAEPITHELIAL NEOPLASIA.Methods: In a before-after clinical trial, patients with histologic evidence of intraepithelial neoplosia identified by tumor excision were studied. Following surgical excision, TOPICAL 5-FU 2% in artificial tear was administered twice daily for one month, and continued daily for another month.The presence or absence of clinically evident INTRAEPITHELIAL NEOPLASIA was evaluated after treatment.Patients were also monitored for adverse reactions to TOPICAL 5-FU.Results: All patients were disease-free with a mean follow up of 14.2 months (range 7-18 month) and no adverse reactions with 2% TOPICAL 5-FU were noted. Conclusions: TOPICAL 5-FU 2% is well tolerated and effective in the treatment of CONJUNCTIVAl and CORNEAl INTRAEPITHELIAL NEOPLASIA when used as adjunctive treatment to surgical excision.

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References

میتومایسین C موضعی در درمان نئوپلازی داخل اپی تلیالی ملتحمه ای – قرنیه ای و کارسینوم سلول سنگفرشی

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APA: Copy

ZAMANI, M., & SHARIFIPOUR, FARIDEH. (2004). TOPICAL 5-FLUOROURACIL FOR TREATMENT OF CONJUNCTIVAL OR CORNEAL INTRAEPITHELIAL NEOPLASIA. BINA, 9(4 (36)), 333-336. SID. https://sid.ir/paper/42373/en

Vancouver: Copy

ZAMANI M., SHARIFIPOUR FARIDEH. TOPICAL 5-FLUOROURACIL FOR TREATMENT OF CONJUNCTIVAL OR CORNEAL INTRAEPITHELIAL NEOPLASIA. BINA[Internet]. 2004;9(4 (36)):333-336. Available from: https://sid.ir/paper/42373/en

IEEE: Copy

M. ZAMANI, and FARIDEH SHARIFIPOUR, “TOPICAL 5-FLUOROURACIL FOR TREATMENT OF CONJUNCTIVAL OR CORNEAL INTRAEPITHELIAL NEOPLASIA,” BINA, vol. 9, no. 4 (36), pp. 333–336, 2004, [Online]. Available: https://sid.ir/paper/42373/en

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