KERATOLIMBAL ALLOGRAFT IN TOTAL LIMBAL STEM CELL DEFICIENCY

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BARADARAN RAFIEI ALI REZA; ABD ELAHI ASIEH; JABARPOUR BONIAADI MOHAMMAD HOSSEIN; MIRDEHGHAN S.A.; ZARE JOUSHAGHANI MOHAMMAD; EYN ELAHI B.; JAVADI M.A.; KARIMIAN FARID; JAFARINASAB M.R.

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Journal: BINA Year:2010 | Volume:15 | Issue:3 (60) Page(s): 167-176

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Title

KERATOLIMBAL ALLOGRAFT IN TOTAL LIMBAL STEM CELL DEFICIENCY

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Keywords

KERATOLIMBAL ALLOGRAFTQ3

KLALQ3

LIMBAL STEM CELL DEFICIENCYQ3

IMMUNOSUPRESSIONQ3

Abstract

Purpose: To investigate the outcomes of KERATOLIMBAL ALLOGRAFT (KLAL) for treatment of totallimbalstem cell deficiency (LSCD).Method: Patients with total LSCD and adequate tear production were included. A total of 27 KLAL procedures were performed in 21 eyes of 20 patients with LSCD. Immunosuppression was achived using mycophenolate and cyclosporine. Main outcome measure was improvement in vision; in addition, KLAL survival and post operative complications were studied.Results: Mean follow up period was 22.14±11.83 months (range 6-39). Mean visual acuity improved from 2.53±0.21 to 1.49±0.77 LogMAR (P<0.001).Six KLALs never re-epithelialized and were considered as primary failures. Mean KLAL survival was 14.23±1.5 months. Graft survival rate was 61.9% at 1 year and 31% at 20 months. Complications included corneal ulcers in 6, glaucoma in 2 and scleral thinking in 1 case. Conclusion: KERATOLIMBAL ALLOGRAFT surgery is successful in the short term for visual rehabilitation of patients with totallimbal stem cell deficiency.

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APA: Copy

BARADARAN RAFIEI, ALI REZA, ABD ELAHI, ASIEH, JABARPOUR BONIAADI, MOHAMMAD HOSSEIN, MIRDEHGHAN, S.A., ZARE JOUSHAGHANI, MOHAMMAD, EYN ELAHI, B., JAVADI, M.A., KARIMIAN, FARID, & JAFARINASAB, M.R.. (2010). KERATOLIMBAL ALLOGRAFT IN TOTAL LIMBAL STEM CELL DEFICIENCY. BINA, 15(3 (60)), 167-176. SID. https://sid.ir/paper/42819/en

Vancouver: Copy

BARADARAN RAFIEI ALI REZA, ABD ELAHI ASIEH, JABARPOUR BONIAADI MOHAMMAD HOSSEIN, MIRDEHGHAN S.A., ZARE JOUSHAGHANI MOHAMMAD, EYN ELAHI B., JAVADI M.A., KARIMIAN FARID, JAFARINASAB M.R.. KERATOLIMBAL ALLOGRAFT IN TOTAL LIMBAL STEM CELL DEFICIENCY. BINA[Internet]. 2010;15(3 (60)):167-176. Available from: https://sid.ir/paper/42819/en

IEEE: Copy

ALI REZA BARADARAN RAFIEI, ASIEH ABD ELAHI, MOHAMMAD HOSSEIN JABARPOUR BONIAADI, S.A. MIRDEHGHAN, MOHAMMAD ZARE JOUSHAGHANI, B. EYN ELAHI, M.A. JAVADI, FARID KARIMIAN, and M.R. JAFARINASAB, “KERATOLIMBAL ALLOGRAFT IN TOTAL LIMBAL STEM CELL DEFICIENCY,” BINA, vol. 15, no. 3 (60), pp. 167–176, 2010, [Online]. Available: https://sid.ir/paper/42819/en

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