COMPARISON OF THE IOP REDUCING EFFECT OF SUBLINGUAL TIMOLOL AND DORZOLAMIDE

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SEDAGHAT M.R.; MORTAZAVI FARD M.; ESMAEILI H.

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Journal: BINA Year:2000 | Volume:5 | Issue:3 Page(s): 252-256

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Title

COMPARISON OF THE IOP REDUCING EFFECT OF SUBLINGUAL TIMOLOL AND DORZOLAMIDE

Author(s)

SEDAGHAT M.R. | MORTAZAVI FARD M. | ESMAEILI H. | Issue Writer Certificate

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Abstract

Objectives: Evaluation of the effectiveness and safety of sublingual timolol 0.5% and dorzolamide 2%. Methods: A randomized, double-masked, placebo controlled study of 120 normal human subjects was carried out in Ghaem Hospital - Mashhad. Volunteers were randomized to receive a single drop of either timolol, dorzolamide or placebo sublingually and IOP measurement were obtained before, 1 hour, and 2 hours after instillation of the drug.Results: The IOP was reduced by a mean of 3.97± 2.07mmHg (21.34%) 2 hours after sublingual timolol instillation (P<0.001). Sublingual dorzolamide and placebo had no ocular hypotensive effect. Conclusion: Sublingual timolol is an effective agent in lowering IOP and maybe an alternative to topical medication in glaucoma. This method of administration in glaucoma needs further study.

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APA: Copy

SEDAGHAT, M.R., MORTAZAVI FARD, M., & ESMAEILI, H.. (2000). COMPARISON OF THE IOP REDUCING EFFECT OF SUBLINGUAL TIMOLOL AND DORZOLAMIDE . BINA, 5(3), 252-256. SID. https://sid.ir/paper/43004/en

Vancouver: Copy

SEDAGHAT M.R., MORTAZAVI FARD M., ESMAEILI H.. COMPARISON OF THE IOP REDUCING EFFECT OF SUBLINGUAL TIMOLOL AND DORZOLAMIDE . BINA[Internet]. 2000;5(3):252-256. Available from: https://sid.ir/paper/43004/en

IEEE: Copy

M.R. SEDAGHAT, M. MORTAZAVI FARD, and H. ESMAEILI, “COMPARISON OF THE IOP REDUCING EFFECT OF SUBLINGUAL TIMOLOL AND DORZOLAMIDE ,” BINA, vol. 5, no. 3, pp. 252–256, 2000, [Online]. Available: https://sid.ir/paper/43004/en

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