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Information Journal Paper

Title

EFFICACY OF CITALOPRAM IN IMPROVING DEPRESSION AND QUALITY OF LIFE IN ACUTE CORONARY SYNDROME

Pages

  67-77

Abstract

 Background and purpose: Prevalence of DEPRESSION in patients with ACUTE CORONARY SYNDROME(ACS) is reported to be 10-40%. Post-ACS DEPRESSION is associated with higher mortality and morbidityin patients, therefore, it requires more attention. Materials and methods: In a clinical trial (conducted in Babol University of Medical Sciences, 2015-2016), 47 hospitalized patients with ACS diagnosis were randomly allocated into two groups. Twenty-four patients in intervention group received 20 mg/day CITALOPRAM and 23 individuals in thecontrol group were followed without receiving CITALOPRAM. Hospital anxiety and DEPRESSION scale (HADS)was applied at weeks 0, 3, and 8. The participants’ QUALITY OF LIFE was evaluated at weeks 0 and 8. Sevenpatients were excluded from the study since they did not return for follow-up. Results: A total of 40 patients was studied including 14 (35%) males and 26 (65%) females. Mean ages of patients in in intervention group and controls were 63. 1± 8. 8 and 68. 4± 7. 9 years, respectively. DEPRESSION and anxiety levels reduced significantly in intervention group and their qualityof life increased in week 8 (P<0. 001). These changes were significantly different between the two groupsin physical functioning, social functioning, emotional well-being and energy/fatigue subscales (P<0. 05). A significant correlation was observed between reduced DEPRESSION and anxiety and improvements inquality of life (P<0. 001). Conclusion: CITALOPRAM could be effective in reducing DEPRESSION and improving QUALITY OF LIFEin ACUTE CORONARY SYNDROME.

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    APA: Copy

    ROBATJAZI, FARZANEH, ZIAIE, NAGHMEH, SALEHI OMRAN, MOHAMMAD TAGHI, JAFARIPOUR, IRAJ, KHOSOOSI NIAKI, MOHAMMAD REZA, MOUDI, SUSSAN, & BIJANI, ALI. (2018). EFFICACY OF CITALOPRAM IN IMPROVING DEPRESSION AND QUALITY OF LIFE IN ACUTE CORONARY SYNDROME. JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, 27(158 ), 67-77. SID. https://sid.ir/paper/44187/en

    Vancouver: Copy

    ROBATJAZI FARZANEH, ZIAIE NAGHMEH, SALEHI OMRAN MOHAMMAD TAGHI, JAFARIPOUR IRAJ, KHOSOOSI NIAKI MOHAMMAD REZA, MOUDI SUSSAN, BIJANI ALI. EFFICACY OF CITALOPRAM IN IMPROVING DEPRESSION AND QUALITY OF LIFE IN ACUTE CORONARY SYNDROME. JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2018;27(158 ):67-77. Available from: https://sid.ir/paper/44187/en

    IEEE: Copy

    FARZANEH ROBATJAZI, NAGHMEH ZIAIE, MOHAMMAD TAGHI SALEHI OMRAN, IRAJ JAFARIPOUR, MOHAMMAD REZA KHOSOOSI NIAKI, SUSSAN MOUDI, and ALI BIJANI, “EFFICACY OF CITALOPRAM IN IMPROVING DEPRESSION AND QUALITY OF LIFE IN ACUTE CORONARY SYNDROME,” JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, vol. 27, no. 158 , pp. 67–77, 2018, [Online]. Available: https://sid.ir/paper/44187/en

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