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Information Journal Paper

Title

STUDY ON THE EFFECT OF HALOTHANS AND PREOXYGENATION ON INTRAOCULAR PRESSURE DURING TRACHEAL INTUBATION

Pages

  34-41

Abstract

 Background and purpose: One of the main aims of anesthesia, particularly in ophtalmic surgeries is rise in intraocular (IOP). On the other hand, in order to have a good air way control during general anesthesia, intubation is necessary. Many studies with different anesthetic agents have been done in order to control the rise of IOP during intubation, while performing anesthesia, but in our study they were not available for us. This study was done in order to evaluate the effect of HALOTHANE with MAC concentration before intravenous injection and preoxygenation on IOP variation due to intubation.Materials and methods: In a clinical trial with sequential sampling and after obtaining approval from the university research ethics committee, 102 patients of 16 to 65 years old, with I, II ASA risk undergoing elective general and orthopedic surgeries, were divided randomly in two HALOTHANE (case) and nonHALOTHANE (Control) groups.The control group (51 patients) were preoxygenated with 100% oxygen for 8 minutes and intubated with the drugs similar to fentanyl, nasdonal and pavelone. Case group was matched with control group for all conditions. Except for the time of preoxygenation, MAC. IOP was measured by schiots tonometer in pre and post intubation. Paired t test and ANOVA test were used for statistical analysis of the obtained data.Results: In this study, IOP did not show any significant difference in pre and post intubation (P<0.05), but the difference in the minutes of one and five after intubation was significant (P=0.001, P<0.001). The highest rate of IOP rise (42.68%) was observed in the first minute after intubation in the control group.Conclusion: Control in the IOP increament with HALOTHANE may be due to more relaxation of eye muscle by HALOTHANE and quickness in more proper reabsorption of equeous humour. Hence, it is recommended that, more absorbant HALOTHANE with MAC concentration be used during intubation and prior to induction of IV anesthesia, at least for 8 minutes along with preoxygenation.

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    APA: Copy

    NASIRI, E., & FARROKHFAR, A.. (2002). STUDY ON THE EFFECT OF HALOTHANS AND PREOXYGENATION ON INTRAOCULAR PRESSURE DURING TRACHEAL INTUBATION. JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, 12(35), 34-41. SID. https://sid.ir/paper/44435/en

    Vancouver: Copy

    NASIRI E., FARROKHFAR A.. STUDY ON THE EFFECT OF HALOTHANS AND PREOXYGENATION ON INTRAOCULAR PRESSURE DURING TRACHEAL INTUBATION. JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2002;12(35):34-41. Available from: https://sid.ir/paper/44435/en

    IEEE: Copy

    E. NASIRI, and A. FARROKHFAR, “STUDY ON THE EFFECT OF HALOTHANS AND PREOXYGENATION ON INTRAOCULAR PRESSURE DURING TRACHEAL INTUBATION,” JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, vol. 12, no. 35, pp. 34–41, 2002, [Online]. Available: https://sid.ir/paper/44435/en

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