COMPARISON BETWEEN THE CYTOTOXIC EFFECTS OF ZINC ON RAJI AND MOLT-4 CELL LINE

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TOKMEH DASHI H.

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Journal: JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES Year:2005 | Volume:15 | Issue:46 Page(s): 25-31

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Title

COMPARISON BETWEEN THE CYTOTOXIC EFFECTS OF ZINC ON RAJI AND MOLT-4 CELL LINE

Author(s)

TOKMEH DASHI H. | Issue Writer Certificate

Keywords

ZINCQ3

RAJI CELLQ4

MOLT-4 CELLQ4

VIABILITYQ4

CYTOTOXICITYQ2

Abstract

Background and purpose: ZINC has important effects on human health, specially on structural and functional activities of immune system. This study was carried out to examine the in vitro cytotoxic effects of ZINC on Raji and Molt-4cell line.Materials and methods: In this study (by cell culture) the cell line was exposed to different concentration of ZINC followed by incubation (37 c, 5% Co2) at various time points (12 to 72 hrs), VIABILITY and proliferation of Raji and MOLT-4 CELLs were then evaluated with florecent (Ethidium-Bromide and Acridine-Orange) staining. Data were analysed using SPSS (Dunet and analysis of varians test).Results: The results showed different responces to different amount of ZINC by The Raji & MOLT-4 CELLs. Concentrations up to 100µM at different incubation time points had no effects on cell line when compared with the controls. With higher concentrations of ZINC (200-500 µM) VIABILITY diminished significantly at 12, 24, ... hrs of incubation times when compared with the controls (p<0.05).Conclusion: We conclude that Zn has dose-dependent cytotoxic effect on Raji and MOLT-4 CELLs.

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APA: Copy

TOKMEH DASHI, H.. (2005). COMPARISON BETWEEN THE CYTOTOXIC EFFECTS OF ZINC ON RAJI AND MOLT-4 CELL LINE. JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, 15(46), 25-31. SID. https://sid.ir/paper/44518/en

Vancouver: Copy

TOKMEH DASHI H.. COMPARISON BETWEEN THE CYTOTOXIC EFFECTS OF ZINC ON RAJI AND MOLT-4 CELL LINE. JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2005;15(46):25-31. Available from: https://sid.ir/paper/44518/en

IEEE: Copy

H. TOKMEH DASHI, “COMPARISON BETWEEN THE CYTOTOXIC EFFECTS OF ZINC ON RAJI AND MOLT-4 CELL LINE,” JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, vol. 15, no. 46, pp. 25–31, 2005, [Online]. Available: https://sid.ir/paper/44518/en

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