METHYLPREDNISOLON ACETATE IN THE MANAGEMENT OF DISTAL URETERAL STONES

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FALAHATKAR S.; MOUSANEZHAD N.A.; SALEHI MOHAMMAD; SHIRI HASAN; NIKPOUR SARA; AKBARPOUR MARZIEH; KHAKI NEGIN

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Journal: JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES Year:2008 | Volume:17 | Issue:62 Page(s): 1-6

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Title

METHYLPREDNISOLON ACETATE IN THE MANAGEMENT OF DISTAL URETERAL STONES

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Keywords

RENAL COLICQ3

METHYLPREDNISOLONQ3

URETERAL STONEQ3

Abstract

Background and Purpose: Acute RENAL COLIC is a common complaint from patients entering the emergency departments. Although, urethral lithotripsy and extracorporeal shock wave lithotripsy are known to be effective, the role of medical-expulsive therapy for the treatment of this disease has not yet been established. This study assessed the clinical efficacy of addition methylprednisol on acetate in the medical-expulsive therapy of distal ureterolithiasis.Materials and Methods: Eighty five (85) consecutive patients with a symptomatic distal urethral stone were included in our study and randomized to one of two home treatment groups. Group A patients (n = 45) received tramadol (50mg bid) and hydrochlorothiazide (50 mg daily) for 21 days, and group B patients (n = 40) were treated with a corticosteroid drug (methylprednisolon acetate 40mg intra- uscular on 0, 7 and 14 days after treatment), in addition to tramadol and hydrochlorothiazide. The treatment duration was 21 days. All patients wearer-evaluated after 21 days with a clinical examination and KUB.Results: The mean stone size was 5.2 mm and 5.8mm in groups A and B respectively (P value>0.05). Both groups had a significant difference in expulsion rate (20(44.4%) for group A and 32 (88%) for group B; (P value<0.001).Conclusion: Our results suggest that the use of a corticosteroid drug in association with tramadol and hydro-cholorothiazid appeared to induce an increase in the expulsion rate.

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APA: Copy

FALAHATKAR, S., MOUSANEZHAD, N.A., SALEHI, MOHAMMAD, SHIRI, HASAN, NIKPOUR, SARA, AKBARPOUR, MARZIEH, & KHAKI, NEGIN. (2008). METHYLPREDNISOLON ACETATE IN THE MANAGEMENT OF DISTAL URETERAL STONES. JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, 17(62), 1-6. SID. https://sid.ir/paper/44551/en

Vancouver: Copy

FALAHATKAR S., MOUSANEZHAD N.A., SALEHI MOHAMMAD, SHIRI HASAN, NIKPOUR SARA, AKBARPOUR MARZIEH, KHAKI NEGIN. METHYLPREDNISOLON ACETATE IN THE MANAGEMENT OF DISTAL URETERAL STONES. JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2008;17(62):1-6. Available from: https://sid.ir/paper/44551/en

IEEE: Copy

S. FALAHATKAR, N.A. MOUSANEZHAD, MOHAMMAD SALEHI, HASAN SHIRI, SARA NIKPOUR, MARZIEH AKBARPOUR, and NEGIN KHAKI, “METHYLPREDNISOLON ACETATE IN THE MANAGEMENT OF DISTAL URETERAL STONES,” JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, vol. 17, no. 62, pp. 1–6, 2008, [Online]. Available: https://sid.ir/paper/44551/en

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