EFFECT OF FE2O3 NANOPARTICLES ON ANXIETY BEHAVIOR AND NOCICEPTION IN ADULT MALE RAT

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

KESMATI M.; KHORSHIDI M.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Journal of Kerman University of Medical Sciences Year:2014 | Volume:21 | Issue:1 Page(s): 1-10

Download Full-Text

Persian Verion

View:

566

Download:

Cites:

Information Journal Paper

Title

EFFECT OF FE2O3 NANOPARTICLES ON ANXIETY BEHAVIOR AND NOCICEPTION IN ADULT MALE RAT

Author(s)

KESMATI M. | KHORSHIDI M. | Issue Writer Certificate

Keywords

ANXIETYQ2

PAINQ2

FE2O3 NANOPARTICLEQ2

RATQ2

Abstract

Background & Aims: Iron is an essential element for correct brain function. Iron deficiency changes some behaviors such as ANXIETY and nociception. Recently, nano-iron, Ferric or ferro oxide (nano-Fe2O3 or Fe3O4), are used in various applications in agriculture, industry and medicine, but their effects on the heath and behavior is not clear. In this study, the effects of Fe2O3 nanoparticles on animal models of ANXIETY and nociception were investigated.Methods: Adult male Wistar RATs (mean weight: 200-250 g) were used in 12 groups: 3 control groups (receiving saline 0.9%) and 9 groups received nano-Fe2O3 in doses of 0.2, 1 and 5 mg/kg, intraperitoneally. Elevated plus maze apparatus and hot-plate and tail-flick tests were used to evaluate ANXIETY and nociception, respectively. Data were analyzed by one-way ANOVA and post hock least significant difference (LSD) and P < 0.05 used as significant level.Results: Fe2O3 nanoparticles with dose addition increased open arm time percent (OAT%) (P<0.05). Locomotor activity, just in dose of 5 mg/kg, increased PAIN delay time in both hot-plate (P<0.01) and tail-flick (P<0.01) tests.Conclusion: Acute administration of Fe2O3 nanoparticle decreases ANXIETY behaviors in elevated plus maze and increases an acute PAIN threshold in both hot-plate and tail-flick tests in RATs.

Cites

No record.

References

No record.

Cite

APA: Copy

KESMATI, M., & KHORSHIDI, M.. (2014). EFFECT OF FE₂O₃ NANOPARTICLES ON ANXIETY BEHAVIOR AND NOCICEPTION IN ADULT MALE RAT. JOURNAL OF KERMAN UNIVERSITY OF MEDICAL SCIENCES, 21(1), 1-10. SID. https://sid.ir/paper/447/en

Vancouver: Copy

KESMATI M., KHORSHIDI M.. EFFECT OF FE₂O₃ NANOPARTICLES ON ANXIETY BEHAVIOR AND NOCICEPTION IN ADULT MALE RAT. JOURNAL OF KERMAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2014;21(1):1-10. Available from: https://sid.ir/paper/447/en

IEEE: Copy

M. KESMATI, and M. KHORSHIDI, “EFFECT OF FE₂O₃ NANOPARTICLES ON ANXIETY BEHAVIOR AND NOCICEPTION IN ADULT MALE RAT,” JOURNAL OF KERMAN UNIVERSITY OF MEDICAL SCIENCES, vol. 21, no. 1, pp. 1–10, 2014, [Online]. Available: https://sid.ir/paper/447/en

Related Journal Papers