A Review on Current Status and Future Potential of Transdermal Patches as a Promising Drug Delivery System

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SAEEDI MAJID; Farmoudeh Ali; Rezaeiroshan Anahita

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Paper Information

Journal: Journal of Mazandaran University of Medical Sciences Year:2019 | Volume:29 | Issue:173 Page(s): 164-175

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Information Journal Paper

Title

A Review on Current Status and Future Potential of Transdermal Patches as a Promising Drug Delivery System

Author(s)

SAEEDI MAJID | Farmoudeh Ali | Rezaeiroshan Anahita | Issue Writer Certificate

Keywords

Transdermal drug delivery systemQ1

reservoir-type patchQ1

matrix-type patchQ1

microneedle patchQ1

Abstract

Transdermal patches are now widely used in topical and Transdermal drug delivery systems (TDDS). Up to now, TDDS has been used in several conditions, such as smoking cessation, analgesic effect, nausea, contraception, and hormone therapy. Basically, there are two types of transdermal patches: the reservoir-type patches and the matrix-type patches. First generation TDDS were designed for delivery of drugs in low-dose. In second-generation delivery systems, drug penetration was increased using chemical enhancers and iontophoresis. Several methods such as microneedles, electroporation, and cavitational ultrasound are used as the third generation of TDDS for targeting their effects to skin’ s barrier layer of stratum corneum. Microneedles are currently studied through clinical trials as suitable delivery system for macromolecules and vaccines, such as insulin and influenza vaccine. This review article describes the structure of different types of transdermal patches and some marketed products. It also introduces a framework for present and future developments of percutaneous drug delivery by transdermal patches.

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References

Prolonged therapy with the anticonvulsant carbamazepine leads to increased plasma clearance of fentanyl

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APA: Copy

SAEEDI, MAJID, Farmoudeh, Ali, & Rezaeiroshan, Anahita. (2019). A Review on Current Status and Future Potential of Transdermal Patches as a Promising Drug Delivery System. JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, 29(173 ), 164-175. SID. https://sid.ir/paper/44824/en

Vancouver: Copy

SAEEDI MAJID, Farmoudeh Ali, Rezaeiroshan Anahita. A Review on Current Status and Future Potential of Transdermal Patches as a Promising Drug Delivery System. JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2019;29(173 ):164-175. Available from: https://sid.ir/paper/44824/en

IEEE: Copy

MAJID SAEEDI, Ali Farmoudeh, and Anahita Rezaeiroshan, “A Review on Current Status and Future Potential of Transdermal Patches as a Promising Drug Delivery System,” JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, vol. 29, no. 173 , pp. 164–175, 2019, [Online]. Available: https://sid.ir/paper/44824/en

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