DRUG UTILIZATION EVALUATION OF PANTOPRAZOLE IN A TEACHINGHOSPITAL IN NORTH OF IRAN, 2016

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Ahmadi Hanieh; AHANGAR NEMATOLLAH; SAGHAFI FATEMEH; ALA SHAHRAM; ESLAMI GOHAR; SALEHIFAR EBRAHIM

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Title

DRUG UTILIZATION EVALUATION OF PANTOPRAZOLE IN A TEACHINGHOSPITAL IN NORTH OF IRAN, 2016

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Keywords

PANTOPRAZOLEQ1

DRUG UTILIZATION EVALUATIONQ1

PROTON PUMP INHIBITORQ1

INTRAVENOUSQ1

Abstract

Background and purpose: PROTON PUMP INHIBITORs (PPIs) are one of the main therapeuticagents for acid-dependent diseases. Inappropriate use of this group of drugs especially INTRAVENOUS formof PANTOPRAZOLE can lead to unnecessary cost. The aim of this study was to assess the IV PANTOPRAZOLEutilization in a teaching hospital in North of Iran. Materials and methods: This cross sectional study was performed within four months in 100patients hospitalized in Ramsar Imam Sajjad Hospital, 2016. Demographic data, type and doses ofPANTOPRAZOLE, risk factors for stress ulcer, and other relevant clinical data were recorded. Appropriate useof PANTOPRAZOLE was assessed according to recommendations provided by Fact Drug Information 2016, Medscape 2016, and UpToDate 2016. Results: Among the patients 54% had indication for receiving a PPI and only 16% had indicationfor parenteral form of PPI. Oral PPIs could have been used in 73% of the patients but they receivedparenteral form of PANTOPRAZOLE. In 92% of IV injections, a vial of 40 mg PANTOPRAZOLE was dissolved in10 ml distilled water and injection was done in less than 10 seconds which was incompatible withguidelines. Conclusion: In current study, utilization of PANTOPRAZOLE was not compatible with guidelines inmost cases, including right indication, right preparation methods and right rate of drug administration.

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APA: Copy

Ahmadi, Hanieh, AHANGAR, NEMATOLLAH, SAGHAFI, FATEMEH, ALA, SHAHRAM, ESLAMI, GOHAR, & SALEHIFAR, EBRAHIM. (2018). DRUG UTILIZATION EVALUATION OF PANTOPRAZOLE IN A TEACHINGHOSPITAL IN NORTH OF IRAN, 2016. JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, 28(162 ), 69-76. SID. https://sid.ir/paper/45042/en

Vancouver: Copy

Ahmadi Hanieh, AHANGAR NEMATOLLAH, SAGHAFI FATEMEH, ALA SHAHRAM, ESLAMI GOHAR, SALEHIFAR EBRAHIM. DRUG UTILIZATION EVALUATION OF PANTOPRAZOLE IN A TEACHINGHOSPITAL IN NORTH OF IRAN, 2016. JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2018;28(162 ):69-76. Available from: https://sid.ir/paper/45042/en

IEEE: Copy

Hanieh Ahmadi, NEMATOLLAH AHANGAR, FATEMEH SAGHAFI, SHAHRAM ALA, GOHAR ESLAMI, and EBRAHIM SALEHIFAR, “DRUG UTILIZATION EVALUATION OF PANTOPRAZOLE IN A TEACHINGHOSPITAL IN NORTH OF IRAN, 2016,” JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, vol. 28, no. 162 , pp. 69–76, 2018, [Online]. Available: https://sid.ir/paper/45042/en

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