APPLICATION OF TRANSDERMAL TESTOSTERONE IN TREATMENT OF MALE HYPOGONADISM

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Tajbakhsh Mahgol; SAEEDI MAJID

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Journal Paper

Paper Information

Journal: JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES Year:2018 | Volume:28 | Issue:165 Page(s): 189-202

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Title

APPLICATION OF TRANSDERMAL TESTOSTERONE IN TREATMENT OF MALE HYPOGONADISM

Author(s)

Tajbakhsh Mahgol | SAEEDI MAJID | Issue Writer Certificate

Keywords

TESTOSTERONEQ2

HYPOGONADISMQ1

TRANSDERMALQ1

PATCHQ1

GELQ3

Abstract

TESTOSTERONE is one of the most important male steroid hormones that plays a key role in thedevelopment of male reproductive tissues. The secretion of this hormone decreases rapidly after age 50. HYPOGONADISM in men is a clinical syndrome that is caused by a defect in the production of TESTOSTERONE, sperm, or both. Several alternative therapies are approved and prescribed according to their efficacy, patient's priorities, and costs. One of these treatments is the TRANSDERMAL administration of TESTOSTERONE. Inthis route, the drug is introduced through attached PATCH with a drug reservoir, through a permeablemembrane, or applied directly on the skin in the form of a GEL or lotion. In different countries, TESTOSTERONEtherapy by TRANSDERMAL administration is rising progressively. TRANSDERMAL TESTOSTERONE delivery by GELsor lotions is the preferred method of some men. The pricing level of these TRANSDERMAL preparations isgenerally higher than commonly available short-acting injectables, but these user friendly methods arestill preferred by many patients. In this study, different types of TRANSDERMAL preparations, mainly PATCH, GEL, and lotion, as well as a brief overview of buccal and intranasal methods are discussed in details.

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APA: Copy

Tajbakhsh, Mahgol, & SAEEDI, MAJID. (2018). APPLICATION OF TRANSDERMAL TESTOSTERONE IN TREATMENT OF MALE HYPOGONADISM. JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, 28(165 ), 189-202. SID. https://sid.ir/paper/45349/en

Vancouver: Copy

Tajbakhsh Mahgol, SAEEDI MAJID. APPLICATION OF TRANSDERMAL TESTOSTERONE IN TREATMENT OF MALE HYPOGONADISM. JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2018;28(165 ):189-202. Available from: https://sid.ir/paper/45349/en

IEEE: Copy

Mahgol Tajbakhsh, and MAJID SAEEDI, “APPLICATION OF TRANSDERMAL TESTOSTERONE IN TREATMENT OF MALE HYPOGONADISM,” JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, vol. 28, no. 165 , pp. 189–202, 2018, [Online]. Available: https://sid.ir/paper/45349/en

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