THE ROLE OF OMICS IN CLINICAL AND PHARMACEUTICAL RESEARCHES

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MEYFOUR ANNA; REZAEI TAVIRANI MOSTAFA

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES Year:2018 | Volume:28 | Issue:161 Page(s): 166-184

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Information Journal Paper

Title

THE ROLE OF OMICS IN CLINICAL AND PHARMACEUTICAL RESEARCHES

Author(s)

MEYFOUR ANNA | REZAEI TAVIRANI MOSTAFA | Issue Writer Certificate

Keywords

PROTEOMICSQ1

GENOMICSQ1

METABOLOMICSQ1

BIOMARKERQ1

PERSONALIZED MEDICINEQ1

OMICSQ1

Abstract

Completion of the human genome project revealed that the molecular mechanisms of cellularresponses to different situations cannot be predicted from the sequence of their genes. Hence, mostbiological researches are focused on the roles of proteins which are much more challenging tasks. OMICStechnologies, instead of analyzing individual components of an organism by conventional biochemicalmethods such as the function of a gene, protein or biochemical reaction, study all the components andtheir interactions within a global site. In the past two decades, OMICS technologies have been used asefficient and powerful tools in almost all aspects of clinical and pharmaceutical researches, includingbiomarker discovery, drug target discovery, evaluation of the efficacy of drugs, safety assessment, andpersonalized medicine. In this article, OMICS technologies such as GENOMICS, transcriptomics, PROTEOMICSand METABOLOMICS, and their advances are reviewed and their applications in clinical and pharmaceuticalresearches, particularly in the areas of drug targets, BIOMARKERs, and PERSONALIZED MEDICINE are discussed.

Cites

Iran’ s Contribution to Human Proteomic Research

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APA: Copy

MEYFOUR, ANNA, & REZAEI TAVIRANI, MOSTAFA. (2018). THE ROLE OF OMICS IN CLINICAL AND PHARMACEUTICAL RESEARCHES. JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, 28(161 ), 166-184. SID. https://sid.ir/paper/45470/en

Vancouver: Copy

MEYFOUR ANNA, REZAEI TAVIRANI MOSTAFA. THE ROLE OF OMICS IN CLINICAL AND PHARMACEUTICAL RESEARCHES. JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2018;28(161 ):166-184. Available from: https://sid.ir/paper/45470/en

IEEE: Copy

ANNA MEYFOUR, and MOSTAFA REZAEI TAVIRANI, “THE ROLE OF OMICS IN CLINICAL AND PHARMACEUTICAL RESEARCHES,” JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, vol. 28, no. 161 , pp. 166–184, 2018, [Online]. Available: https://sid.ir/paper/45470/en

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