THE EFFECT OF SUBSTITUTING IRANIAN WALNUT AS A PART OF PUFA IN THE DIET ON THE SERUM LIPID PROFILE OF MILDLY HYPERCHOLESTEROLEMIC POST- MENOPAUSAL WOMEN

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KIMIAGAR SEYED MASOUD; VELAEI N.; TAVAKKOLI DARESTANI A.

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Journal: Journal of Mazandaran University of Medical Sciences Year:2004 | Volume:14 | Issue:44 Page(s): 21-32

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Title

THE EFFECT OF SUBSTITUTING IRANIAN WALNUT AS A PART OF PUFA IN THE DIET ON THE SERUM LIPID PROFILE OF MILDLY HYPERCHOLESTEROLEMIC POST- MENOPAUSAL WOMEN

Author(s)

KIMIAGAR SEYED MASOUD | VELAEI N. | TAVAKKOLI DARESTANI A. | Issue Writer Certificate

Keywords

WALNUTQ3

HYPERCHOLESTEROLEMIAQ3

ALPHA-LINOLENIC ACID AND LIPID PROFILEQ4

Abstract

Background and purpose: In view of the importance of controlling hyperlipidemia in prevention of cardiovascular disease and due to the conflicting reports on effects of WALNUT on serum lipids, especially triglyceride and HDL-C, this research was performed in order to determine the effect of substituting WALNUT as a part of PUFA in the diet on the serum lipid profile of mildly hypercholesterolemic post- menopausal women.Materials and methods: The study was a before and after clinical trial type, on 8 post- menopause women with mild HYPERCHOLESTEROLEMIA (Total cholesterol between 200-240 mg/dl, HDL-C over 40 mg/dl). Anthropometric measurements before the study and after four weeks of intervention were made. Dietary pattern was assessed by a 24- hour dietary recall questionnaire, three days before study, two days in the 2nd week and two days in the 4th week. Dietary data were analyzed with Nutririonist IV Software. After analysis of the patients diet, total fat, PUFA, MUFA and SFA were determined. WALNUT fat was substituted as a part of PUFA for one third of total fat. All patients received WALNUT for four weeks. In order to determine serum cholesterol, triglyceride, LDL-C and HDL-C overnight fasting blood samples were collected in the beginning and at the 4th week of the study. Total cholesterol, triglyceride and HDL-C were measured by enzymatic methods and LDL-C was calculated by subtracting with the Friedewald equation. Statistical analysis: Comparisons were made using parired t test and ANOVA RM.Results: During four weeks of the study no significant changes were observed in body mass index and waist to hip ratio. Total cholesterol and LDL-C were significantly decreased to 14.8% (P<0.001) and 25% (P<0.01) respectively. LDL-C, HDL-C was significantly reduced (P<0.05) after four weeks. Other changes in the other lipidemic parameters were non-significant.No Significant differences were found among dietary intake of carbohydrate, protein, fiber, total fat, saturated fatty acid, MUFA, PUFA (linoleic) during the 2nd and 4th week, only linolenic acid was significantly higher (P<0.000).Conclusion: Substituting WALNUT as a part of dietary PUFA resulted in total cholesterol and LDL-C reduction and lowered LDL-C, HDL-C ratio.

Cites

THE EFFECT OF THE ALCOHOLIC EXTRACT OF WALNUT ON THE TESTIS TISSUE OF ADULT MALE RATS

References

تاثیر مصرف ماهی چرب شمال و جنوب ایران بر لیپیدهای سرم و فشار خون مردان جوان سالم

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APA: Copy

KIMIAGAR, SEYED MASOUD, VELAEI, N., & TAVAKKOLI DARESTANI, A.. (2004). THE EFFECT OF SUBSTITUTING IRANIAN WALNUT AS A PART OF PUFA IN THE DIET ON THE SERUM LIPID PROFILE OF MILDLY HYPERCHOLESTEROLEMIC POST- MENOPAUSAL WOMEN. JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, 14(44), 21-32. SID. https://sid.ir/paper/45544/en

Vancouver: Copy

KIMIAGAR SEYED MASOUD, VELAEI N., TAVAKKOLI DARESTANI A.. THE EFFECT OF SUBSTITUTING IRANIAN WALNUT AS A PART OF PUFA IN THE DIET ON THE SERUM LIPID PROFILE OF MILDLY HYPERCHOLESTEROLEMIC POST- MENOPAUSAL WOMEN. JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2004;14(44):21-32. Available from: https://sid.ir/paper/45544/en

IEEE: Copy

SEYED MASOUD KIMIAGAR, N. VELAEI, and A. TAVAKKOLI DARESTANI, “THE EFFECT OF SUBSTITUTING IRANIAN WALNUT AS A PART OF PUFA IN THE DIET ON THE SERUM LIPID PROFILE OF MILDLY HYPERCHOLESTEROLEMIC POST- MENOPAUSAL WOMEN,” JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, vol. 14, no. 44, pp. 21–32, 2004, [Online]. Available: https://sid.ir/paper/45544/en

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