EFFECT OF ORAL MAGNESIUM CITRATE SUPPLEMENT ON LUNG FUNCTION AND MAGNESIUM LEVEL IN PATIENTS WITH ASTHMA

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FATHI NARGES; HOSSEINI SEYED AHMAD; TAVAKKOL HESHMATOLLAH; KHODADADY ALI; TABESH HAMED

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Journal: JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES Year:2014 | Volume:24 | Issue:111 Page(s): 44-51

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Title

EFFECT OF ORAL MAGNESIUM CITRATE SUPPLEMENT ON LUNG FUNCTION AND MAGNESIUM LEVEL IN PATIENTS WITH ASTHMA

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Keywords

MAGNESIUM CITRATEQ2

ASTHMAQ2

Abstract

Background and purpose: ASTHMA is a chronic inflammatory disorder of the airway associated with airway hyper responsiveness that leads to recurrent episodes of wheezing, breathlessness, chest tightness, and coughing. Low dietary magnesium (Mg) could influence the occurrence and management of ASTHMA. Mg is an essential element of human body, but its benefit for pulmonary function is not completely known.Material and Methods: This randomized, double-blind, placebo controlled, clinical trial was performed on 112 patients with mild and moderate persistent ASTHMA. The diagnosis was based on clinical history and spirometric pulmonary testing. Blood samples were taken and level magnesium was measured. Participants were randomly assigned to consume either 340 mg of Mg as Mg citrate per day or placebo for two months. Each outcome was compared within treatment groups by paired t test for parametric data and the Wilcoxon signed rank test for non-parametric data. The significance level was considered as P<0.05.Results: After two months administration of oral Mg supplementation, significant changes were observed in FVC (P=0.002), FEV1 (P=0.000), FEV1/FVC ratio (P=0.000). The FVC, FEV1 have increased and the FEV1/FVC ratio value has decreased significantly.Conclusions: This study provides evidence that oral magnesium supplementation can improve lung function in patients with mild and moderate ASTHMA.

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APA: Copy

FATHI, NARGES, HOSSEINI, SEYED AHMAD, TAVAKKOL, HESHMATOLLAH, KHODADADY, ALI, & TABESH, HAMED. (2014). EFFECT OF ORAL MAGNESIUM CITRATE SUPPLEMENT ON LUNG FUNCTION AND MAGNESIUM LEVEL IN PATIENTS WITH ASTHMA. JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, 24(111), 44-51. SID. https://sid.ir/paper/45807/en

Vancouver: Copy

FATHI NARGES, HOSSEINI SEYED AHMAD, TAVAKKOL HESHMATOLLAH, KHODADADY ALI, TABESH HAMED. EFFECT OF ORAL MAGNESIUM CITRATE SUPPLEMENT ON LUNG FUNCTION AND MAGNESIUM LEVEL IN PATIENTS WITH ASTHMA. JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2014;24(111):44-51. Available from: https://sid.ir/paper/45807/en

IEEE: Copy

NARGES FATHI, SEYED AHMAD HOSSEINI, HESHMATOLLAH TAVAKKOL, ALI KHODADADY, and HAMED TABESH, “EFFECT OF ORAL MAGNESIUM CITRATE SUPPLEMENT ON LUNG FUNCTION AND MAGNESIUM LEVEL IN PATIENTS WITH ASTHMA,” JOURNAL OF MAZANDARAN UNIVERSITY OF MEDICAL SCIENCES, vol. 24, no. 111, pp. 44–51, 2014, [Online]. Available: https://sid.ir/paper/45807/en

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