THE EFFECT OF ENDURANCE TRAINING UNDER MICROGRAVITY CONDITION ON SERUM LEVEL OFBRAIN-DERIVED NEUROTROPHIC FACTOR IN MALE RATS

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ASADI GOLZAR MOHAMMAD; KAZEMI ALI; KHALEDI NEDA; HAJEBRAHIMI ZAHRA; NIKBAKHT VAHID; YARI MORTEZA

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Journal: MEDICAL JOURNAL OF TABRIZ UNIVERSITY OF MEDICAL SCIENCES Year:2019 | Volume:40 | Issue:5 Page(s): 16-22

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Title

THE EFFECT OF ENDURANCE TRAINING UNDER MICROGRAVITY CONDITION ON SERUM LEVEL OFBRAIN-DERIVED NEUROTROPHIC FACTOR IN MALE RATS

Author(s)

Keywords

MICROGRAVITYQ1

BDNFQ1

ENDURANCE TRAININGQ1

HIND-LIMB SUSPENSIONQ1

RATQ2

Abstract

Background: Exposure to MICROGRAVITY condition such as space, bed rest and other MICROGRAVITY environmentslead to several neuromuscular problems. The purpose of this study is to investigate the effect of four weeksendurance training under MICROGRAVITY condition on serum level of Brain-derived neurotrophic factor in male RATs. Methods: In this regard, 36 six-week-old male Wistar RATs (weight range 175 ± 15 gr) were randomly selectedand divided into four groups including suspension group (n=10), ENDURANCE TRAINING group (n= 6), ENDURANCE TRAINING+ suspension (n=10), control (n=10) and were examined for four weeks. To simulate MICROGRAVITY condition onEarth, HIND-LIMB SUSPENSION model was used for four weeks. After collecting blood samples from left ventricles ofrats and separating serum BDNF levels were measured by ELISA kit. Results: our results showed that serum levels of BDNF in ENDURANCE TRAINING with suspension group compare toother groups significantly increased (P<0. 05). Conclusion: Based on the present results, it seems that ENDURANCE TRAINING under MICROGRAVITY conditioncould reduce the neuromuscular problems induced by MICROGRAVITY. Also this type of training like exerciseswith anti-gravity treadmills can be used for other physiological condition similar to astronauts, such as theelderly and patient on bed rest and people with spinal cord injury.

Cites

Comparison of the effects of eight weeks of resistance training and ginseng supplementation on growth hormone and insulin resistance in Syrian male mice under lower extremity suspension conditions

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APA: Copy

ASADI GOLZAR, MOHAMMAD, KAZEMI, ALI, KHALEDI, NEDA, HAJEBRAHIMI, ZAHRA, NIKBAKHT, VAHID, & YARI, MORTEZA. (2019). THE EFFECT OF ENDURANCE TRAINING UNDER MICROGRAVITY CONDITION ON SERUM LEVEL OFBRAIN-DERIVED NEUROTROPHIC FACTOR IN MALE RATS. MEDICAL JOURNAL OF TABRIZ UNIVERSITY OF MEDICAL SCIENCES, 40(5 ), 16-22. SID. https://sid.ir/paper/46530/en

Vancouver: Copy

ASADI GOLZAR MOHAMMAD, KAZEMI ALI, KHALEDI NEDA, HAJEBRAHIMI ZAHRA, NIKBAKHT VAHID, YARI MORTEZA. THE EFFECT OF ENDURANCE TRAINING UNDER MICROGRAVITY CONDITION ON SERUM LEVEL OFBRAIN-DERIVED NEUROTROPHIC FACTOR IN MALE RATS. MEDICAL JOURNAL OF TABRIZ UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2019;40(5 ):16-22. Available from: https://sid.ir/paper/46530/en

IEEE: Copy

MOHAMMAD ASADI GOLZAR, ALI KAZEMI, NEDA KHALEDI, ZAHRA HAJEBRAHIMI, VAHID NIKBAKHT, and MORTEZA YARI, “THE EFFECT OF ENDURANCE TRAINING UNDER MICROGRAVITY CONDITION ON SERUM LEVEL OFBRAIN-DERIVED NEUROTROPHIC FACTOR IN MALE RATS,” MEDICAL JOURNAL OF TABRIZ UNIVERSITY OF MEDICAL SCIENCES, vol. 40, no. 5 , pp. 16–22, 2019, [Online]. Available: https://sid.ir/paper/46530/en

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