STUDY ON SERUMMAGNESIUM LEVEL IN ALZHEIMER DISEASE AND ITS RELATIONSHIP WITH THE STAGE OF DISEASE

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SADRALDINI SEYED ALI; FARHODI MAHDI; MAJIDI JAFAR; MOOSAVI MOHAMMAD; MEHDIZADEH ROBAB

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Journal: MEDICAL JOURNAL OF TABRIZ UNIVERSITY OF MEDICAL SCIENCES Year:2010 | Volume:32 | Issue:5 Page(s): 57-62

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Title

STUDY ON SERUMMAGNESIUM LEVEL IN ALZHEIMER DISEASE AND ITS RELATIONSHIP WITH THE STAGE OF DISEASE

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Keywords

ALZHEIMER'S DISEASEQ2

MAGNESIUMQ2

DEMENTIAQ2

Abstract

Background and Objectives: Alzheimer disease is a neurodegenerative disorder, that characterized by memory loss and cognitive functions. The aim purpose of this study was to evaluate the serum MAGNESIUM level in Alzheimer patient and its relationship with diseases severity.Materials and Methods: In a case-control study, 69 patients with AD (ALZHEIMER'S DISEASE) were studied in 15 month period. Seventy one age and sex-matched healthy person also included as controls. Disease severity of was determined by global decay score (GDS). A serum MAGNESIUM level was measured by Atomic Absorption Method. In the patient and control groups The evaluated relationship between serum MAGNESIUM levels with disease severity.Results: Sixty nine patients (M/F=37/34, mean age 71.12±5.81 years) and 71 healthy persons (38/31, M/F) mean age (69.73±5.18 year) were enrolled in this study. Serum MAGNESIUM level in case and control groups was 1.7±0.2 ppm and 1.8±0.3 respectively and it was significantly lower in AD patients (P=0.001). There was no meaningful relationship between MAGNESIUM level and disease severity (P=0.75).Conclusion: This study showed a statistically meaningful difference between serum MAGNESIUM level in patient with AD and healthy individuals but there was no relation between the level and disease severity.

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APA: Copy

SADRALDINI, SEYED ALI, FARHODI, MAHDI, MAJIDI, JAFAR, MOOSAVI, MOHAMMAD, & MEHDIZADEH, ROBAB. (2010). STUDY ON SERUMMAGNESIUM LEVEL IN ALZHEIMER DISEASE AND ITS RELATIONSHIP WITH THE STAGE OF DISEASE. MEDICAL JOURNAL OF TABRIZ UNIVERSITY OF MEDICAL SCIENCES, 32(5), 57-62. SID. https://sid.ir/paper/47115/en

Vancouver: Copy

SADRALDINI SEYED ALI, FARHODI MAHDI, MAJIDI JAFAR, MOOSAVI MOHAMMAD, MEHDIZADEH ROBAB. STUDY ON SERUMMAGNESIUM LEVEL IN ALZHEIMER DISEASE AND ITS RELATIONSHIP WITH THE STAGE OF DISEASE. MEDICAL JOURNAL OF TABRIZ UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2010;32(5):57-62. Available from: https://sid.ir/paper/47115/en

IEEE: Copy

SEYED ALI SADRALDINI, MAHDI FARHODI, JAFAR MAJIDI, MOHAMMAD MOOSAVI, and ROBAB MEHDIZADEH, “STUDY ON SERUMMAGNESIUM LEVEL IN ALZHEIMER DISEASE AND ITS RELATIONSHIP WITH THE STAGE OF DISEASE,” MEDICAL JOURNAL OF TABRIZ UNIVERSITY OF MEDICAL SCIENCES, vol. 32, no. 5, pp. 57–62, 2010, [Online]. Available: https://sid.ir/paper/47115/en

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