ANTIBIOTIC RESISTANCE PATTERN AGAINST FLUOROQUINOLONES AMONG ESCHERICHIA COLI ISOLATED FROM ICU AND OUT- PATIENT CLINIC ADMITTED PATIENTS WITH URINARY TRACT INFECTION

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MAHDAVI ARMITA; NAHAEI M.R.; AKHI M.T.; AKHI MEHRYAR; AKBARI DIBAVAR M.

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Paper Information

Journal: MEDICAL JOURNAL OF TABRIZ UNIVERSITY OF MEDICAL SCIENCES Year:2009 | Volume:31 | Issue:3 Page(s): 91-96

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Title

ANTIBIOTIC RESISTANCE PATTERN AGAINST FLUOROQUINOLONES AMONG ESCHERICHIA COLI ISOLATED FROM ICU AND OUT- PATIENT CLINIC ADMITTED PATIENTS WITH URINARY TRACT INFECTION

Author(s)

Keywords

ANTIBIOTICQ3

RESISTANCEQ3

ESCHERICHIA COLIQ2

FLUOROQUINOLONQ2

URINARY TRACT INFECTIONSQ3

Abstract

Background and Objectives: Widespread use of FLUOROQUINOLONes has resulted in an increasing incidence of RESISTANCE to these agents. Therefore ANTIBIOTIC RESISTANCE surveillance has a great importance. This study was carried out to evaluate the ANTIBIOTIC resistant pattern of ESCHERICHIA COLI isolates against FLUOROQUINOLONes from ICU and out- patient clinic admitted patients with urinary tract infection in Imam Hospital of Tabriz Material and Methods: Urine samples were taken and E. coli were isolated by conventional laboratory methods. The isolated strains were testes by Disk Agar Diffusion (DAD) method and broth macro-dilution method (MIC) according to the CLSI guidelines.Results: A total of hundred E. coli were isolated from urine samples. According to the results of DAD method 57 (57%) were resistant to nalidixic acid, 34 (34%) to norfoloxacin, 33 (33%) to ciprofloxacin and 30 (30%) to ofloxacin. Also 2 (2%) of isolates revealed intermediate RESISTANCE to ofloxacin. By broth macro-dilution 41% were resistant to ciprofloxacin (MIC≥4mg/ml), while 6 isolates had intermediate RESISTANCE pattern (MIC=2 mg/ml) and 53 isolates were sensitive (MIC≤1 mg/ml) to ciprofloxacin.Conclusion: Our results revealed a high level of RESISTANCE against FLUOROQUINOLONes. It would be because of unjustified ANTIBIOTIC usage. To overcome this problem inadvertent prescription should be limited and ANTIBIOTICs should be administered based of microorganism sensitivity patterns.

Cites

FREQUENCY OF QNRA AND QNRB CIPROFLOXACIN-RESISTANT GENES IN ESCHERCHIA COLI STRAINS ISOLATED FROM URINARY TRACT INFECTIONS IN ESTAHBAN-HOSPITALS IN FARS PROVINCE

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APA: Copy

MAHDAVI, ARMITA, NAHAEI, M.R., AKHI, M.T., AKHI, MEHRYAR, & AKBARI DIBAVAR, M.. (2009). ANTIBIOTIC RESISTANCE PATTERN AGAINST FLUOROQUINOLONES AMONG ESCHERICHIA COLI ISOLATED FROM ICU AND OUT- PATIENT CLINIC ADMITTED PATIENTS WITH URINARY TRACT INFECTION. MEDICAL JOURNAL OF TABRIZ UNIVERSITY OF MEDICAL SCIENCES, 31(3), 91-96. SID. https://sid.ir/paper/47279/en

Vancouver: Copy

MAHDAVI ARMITA, NAHAEI M.R., AKHI M.T., AKHI MEHRYAR, AKBARI DIBAVAR M.. ANTIBIOTIC RESISTANCE PATTERN AGAINST FLUOROQUINOLONES AMONG ESCHERICHIA COLI ISOLATED FROM ICU AND OUT- PATIENT CLINIC ADMITTED PATIENTS WITH URINARY TRACT INFECTION. MEDICAL JOURNAL OF TABRIZ UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2009;31(3):91-96. Available from: https://sid.ir/paper/47279/en

IEEE: Copy

ARMITA MAHDAVI, M.R. NAHAEI, M.T. AKHI, MEHRYAR AKHI, and M. AKBARI DIBAVAR, “ANTIBIOTIC RESISTANCE PATTERN AGAINST FLUOROQUINOLONES AMONG ESCHERICHIA COLI ISOLATED FROM ICU AND OUT- PATIENT CLINIC ADMITTED PATIENTS WITH URINARY TRACT INFECTION,” MEDICAL JOURNAL OF TABRIZ UNIVERSITY OF MEDICAL SCIENCES, vol. 31, no. 3, pp. 91–96, 2009, [Online]. Available: https://sid.ir/paper/47279/en

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