EFFECTIVE FACTORS OF OUTCOME IN CHILDREN WITH ACUTE LUNG INJURY

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JAFARI ROUHI AMIR HOSSEIN; SAMADI MAHMOUD; TAGHIZADIEH ALI; NAJJARI MARYAM; KHALOUEIPOUR MAHMOUD

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Journal: Medical Journal of Tabriz University of Medical Sciences Year:2012 | Volume:34 | Issue:3 Page(s): 27-31

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Title

EFFECTIVE FACTORS OF OUTCOME IN CHILDREN WITH ACUTE LUNG INJURY

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Keywords

ACUTE LUNG INJURYQ2

PROGNOSISQ3

PEDIATRIC RISK OF MORTALITY SCOREQ2

Abstract

Background and Objectives: By now, numerous studied have tried to find prognostic factors in patients with ACUTE LUNG INJURY (ALI); however the available data are controversial. The aim of the present study was to determine effective factors of outcome in children with ALI.Materials and Methods: In an observational cross-sectional study, 64 pediatric patients with ALI were recruited in a 22-month period in Tabriz Children’s Hospital. The pediatric Intensive Care Unit (PICU) outcome was determined and accordingly the patients were allocated in two groups; discharged patients and deceased. Patients’ characteristics including age and gender, underlying disorders, parameters of mechanical ventilations, arterial blood gass, organ involvement, presence of acute respiratory distress syndrome (ARDS) and pediatric risk of mortality (PRISM) score were compared between the two groups.Results: The PICU mortality rate was 51.6%. Independent predictive factors of mortality were higher (more negative) base excess (BE) higher positive end-expiratory pressure (PEEP) and peak inspiratory pressure (PIP), and higher on-admission PRISM score, as well as presence of other organ involvement and ARDS. Parameters such as age, gender, underlying disorders and length of stay, PaO2 and PaCO2 were not significantly different between the two groups. In multivariate study, however, high PRISM score was the only dependent predictor of mortality (³13.5, sensitivity: 75.8%, specificity: 90.3%). Conclusion: The PRISM score was the only reliable predictor of PICU-mortality in pediatric patients with ALI.

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PROGNOSTIC FACTORS OF OUTCOME IN CHILDREN WITH ACUTE RESPIRATORY DISTRESS SYNDROME

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APA: Copy

JAFARI ROUHI, AMIR HOSSEIN, SAMADI, MAHMOUD, TAGHIZADIEH, ALI, NAJJARI, MARYAM, & KHALOUEIPOUR, MAHMOUD. (2012). EFFECTIVE FACTORS OF OUTCOME IN CHILDREN WITH ACUTE LUNG INJURY. MEDICAL JOURNAL OF TABRIZ UNIVERSITY OF MEDICAL SCIENCES, 34(3), 27-31. SID. https://sid.ir/paper/47499/en

Vancouver: Copy

JAFARI ROUHI AMIR HOSSEIN, SAMADI MAHMOUD, TAGHIZADIEH ALI, NAJJARI MARYAM, KHALOUEIPOUR MAHMOUD. EFFECTIVE FACTORS OF OUTCOME IN CHILDREN WITH ACUTE LUNG INJURY. MEDICAL JOURNAL OF TABRIZ UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2012;34(3):27-31. Available from: https://sid.ir/paper/47499/en

IEEE: Copy

AMIR HOSSEIN JAFARI ROUHI, MAHMOUD SAMADI, ALI TAGHIZADIEH, MARYAM NAJJARI, and MAHMOUD KHALOUEIPOUR, “EFFECTIVE FACTORS OF OUTCOME IN CHILDREN WITH ACUTE LUNG INJURY,” MEDICAL JOURNAL OF TABRIZ UNIVERSITY OF MEDICAL SCIENCES, vol. 34, no. 3, pp. 27–31, 2012, [Online]. Available: https://sid.ir/paper/47499/en

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