THE EFFECT OF HYPERTHYROIDISM ON ADRENAL CORTEX HORMONES

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TABER M.; MESRIPOUR M.; FERDOSY M.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Journal: Medical Journal of Tabriz University of Medical Sciences Year:2004 | Volume:- | Issue:60 Page(s): 32-36

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Title

THE EFFECT OF HYPERTHYROIDISM ON ADRENAL CORTEX HORMONES

Author(s)

TABER M. | MESRIPOUR M. | FERDOSY M. | Issue Writer Certificate

Keywords

THYROID GLANDQ3

ADRENAL GLANDQ3

T4Q3

T3Q4

TSHQ4

17-KETOSTEROIDSQ4

17-OH STEROIDSQ4

Abstract

Background and Objectives: The most important body control systems are endocrine glands which have ability to regulate cell functions by different ways. Multiple factors can affect this regulation, such as effects of endocrine hormones on each other. In this study, we evaluate effects of thyroid hormones on adrenal cortex secretion. Urine 17-0HKS as glucocorticoid metabolie and urine 17-CS as androgen metabolite, were measured. Materials and Methods: This study was done on 100 healthy volunteers and results compared with 100 hyperthyroid patients. D, T4, TSH, 17-KETOSTEROIDS and 17-0H steroids were measured. There was a positive correlation between D and T4 and urine 17-KS in patients with hyperthyroidism (r=0.64-0.72) and a negative correlation between TSH and urine 17-KS (r=0.74). Results: Urine 17-0HKS levels in healthy volunteers were 2-9.6 µg/mg creatinine (mean 5.4±1.87) and in hyperthyroid patients was 9.2-17, µg/mg creatinine (mean 12.5±3.2) (p<0.0l). Urine 17-KS levels in healthy volunteers were 1.5-15µg/mg creatinine (mean 5.85±2.1) and in hyperthyroid patients were 15.1-23 (mean 17.9±2.87) (p<0.01). In statistical analysis by regression line method in these two endocrine glands hormones, there was a positive correlation between T3 and 17-OHKS (r = 0.72) and D and 17-KS (r=0.74) and a negative correlation between TSH with 17-OHKS and 17-KS (r=0.74). However there were not any correlation between T4 with 17-OHKS and 17-KS in healthy volunteers. Conclusion: These results indicated that increase of thyroid hormones have some effects on adrenal cortex secretion, which may suggest different ways for treatment of adrenal cortex secretion disorders.

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APA: Copy

TABER, M., MESRIPOUR, M., & FERDOSY, M.. (2004). THE EFFECT OF HYPERTHYROIDISM ON ADRENAL CORTEX HORMONES. MEDICAL JOURNAL OF TABRIZ UNIVERSITY OF MEDICAL SCIENCES, -(60), 32-36. SID. https://sid.ir/paper/47547/en

Vancouver: Copy

TABER M., MESRIPOUR M., FERDOSY M.. THE EFFECT OF HYPERTHYROIDISM ON ADRENAL CORTEX HORMONES. MEDICAL JOURNAL OF TABRIZ UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2004;-(60):32-36. Available from: https://sid.ir/paper/47547/en

IEEE: Copy

M. TABER, M. MESRIPOUR, and M. FERDOSY, “THE EFFECT OF HYPERTHYROIDISM ON ADRENAL CORTEX HORMONES,” MEDICAL JOURNAL OF TABRIZ UNIVERSITY OF MEDICAL SCIENCES, vol. -, no. 60, pp. 32–36, 2004, [Online]. Available: https://sid.ir/paper/47547/en

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