EFFECT OF VIT.C, AND VIT.E ON SERUM LEVELS OF LIPIDS AND LIPOPROTEINS IN SMOKERS

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TOUHIDI MOHAMMAD; RAHBANI NOUBAR M.

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Journal: PHARMACEUTICAL SCIENCES Year:2000 | Volume:- | Issue:3 Page(s): 17-24

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Title

EFFECT OF VIT.C, AND VIT.E ON SERUM LEVELS OF LIPIDS AND LIPOPROTEINS IN SMOKERS

Author(s)

TOUHIDI MOHAMMAD | RAHBANI NOUBAR M. | Issue Writer Certificate

Keywords

LIPIDSQ3

LIPOPROTEINSQ3

VITAMIN EQ2

VITAMIN CQ2

SMOKINGQ3

Abstract

The alteration in serum levels of LIPIDS and LIPOPROTEINS in smokers have been reported by many workers. Cigarette smoke causes increased production of free radicals and oxidative stress which lead to lipid peroxdation. Antioxidants play an important role in reduction of the lipid peroxidation. Vitamine E and vitamines. C are most important antioxidant in the human. In this study effects of these vitamines on the serum levels of LIPIDS and LIPOPROTEINS in smokers were estimated.Sixty males, SMOKING more than Six cigarette per day at least for one year, were selected. The selected person was divided into three groups. The first group received Vit. C and Vit E together.Second group Vit. E and third group Vit.C for30days.Beforeandafterrecievingthe vitamines , serum levels of LIPIDS (cholesterol and triglyceride) and LIPOPROTEINS (LDL-C, VLDL-C and HDL- C) were measured by standard methods and HDL-C/LDL-Cratio calculated., by statistical analysis the results obtained in the two steps were compared with each others.In the first group after receiving vitamine E and Vit. C significant reduction in the serum levels of total cholesterol, triglyceride, VLDL-C and LDL-C and marked elevation in those of HLD-C and HDL-C/LDL-C ratio were observed (P<0.05 in all cases). In the second group receiving only Vit. E significant decrease in the serum levels of total cholesterol and LDL-C were noticed (P<0.05 in both cases.). In the third group receiving only Vit. C a maked reduction in the serum levels of total cholesterol, VLDL-C and significant elevation in those of HDL-C/LDL-C ratio and HDL-C were found (P<0.05 in all cases). No significant changes were noticed in the cases of the other parameters. It was concluded that the use of supplementary antioxidant vitamines (E+C) by prevention of LIPIDS and LIPOPROTEINS oxidation decline their concentrations in plasma.

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APA: Copy

TOUHIDI, MOHAMMAD, & RAHBANI NOUBAR, M.. (2000). EFFECT OF VIT.C, AND VIT.E ON SERUM LEVELS OF LIPIDS AND LIPOPROTEINS IN SMOKERS. PHARMACEUTICAL SCIENCES, -(3), 17-24. SID. https://sid.ir/paper/48517/en

Vancouver: Copy

TOUHIDI MOHAMMAD, RAHBANI NOUBAR M.. EFFECT OF VIT.C, AND VIT.E ON SERUM LEVELS OF LIPIDS AND LIPOPROTEINS IN SMOKERS. PHARMACEUTICAL SCIENCES[Internet]. 2000;-(3):17-24. Available from: https://sid.ir/paper/48517/en

IEEE: Copy

MOHAMMAD TOUHIDI, and M. RAHBANI NOUBAR, “EFFECT OF VIT.C, AND VIT.E ON SERUM LEVELS OF LIPIDS AND LIPOPROTEINS IN SMOKERS,” PHARMACEUTICAL SCIENCES, vol. -, no. 3, pp. 17–24, 2000, [Online]. Available: https://sid.ir/paper/48517/en

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