ASSOCIATION OF URIC ACID AND ALBUMINURIA IN PATIENTS WITH TYPE 2 DIABETES

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ZIAEI AMIR; SHEYKH ALESLAMI H.; SARRESHTEHDARI M.; JAVADI MARYAM; KHOUEINIHA H.

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Journal: Journal of Inflammatory Diseases Year:2008 | Volume:12 | Issue:1 (46) Page(s): 16-20

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Title

ASSOCIATION OF URIC ACID AND ALBUMINURIA IN PATIENTS WITH TYPE 2 DIABETES

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Keywords

URIC ACIDQ2

ALBUMINURIAQ3

TYPE 2 DIABETESQ2

Abstract

Background: High serum URIC ACID is associated with kidney damage manifested by glomerular sclerosis, hypertrophy and ALBUMINURIA in animal models.Objective: To evaluate the relationship between elevated serum URIC ACID and urinary albumin/creatinine ratio in TYPE 2 DIABETES.Methods: In this cross-sectional study, 290 patients (130 males and 160 females) with TYPE 2 DIABETES were recruited for measuring, cholesterol, triglycerides, URIC ACID and albumin/creatinine ratio (ACR). The data obtained for albumin/creatinine ratio were expressed as mean±SD or percentage and a P value £0.05 was considered as significant. One-way analysis of variance and Pearson correlation coefficient were used for statistical studies.Findings: The mean ages of patients were 58.2±8.6 years. URIC ACID levels for norrnalbuminuria, microalbuminuria and marcoalbuminuria were (5.1±0.7, 6.3±1.1, and 8.1±1.3 mg/dl, respectively). While the URIC ACID level in men was shown to have a positive correlation with natural logarithmic ACR [Ln (ACR)], ( d=0.53, p<0.05), a positive correlation with both triglycerides and Ln (ACR) was found among women (0=0.263, P<0.01).Conclusion: Based on our data, serum URIC ACID was found to be independently correlated with urinary ACR in patients with TYPE 2 DIABETES.

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APA: Copy

ZIAEI, AMIR, SHEYKH ALESLAMI, H., SARRESHTEHDARI, M., JAVADI, MARYAM, & KHOUEINIHA, H.. (2008). ASSOCIATION OF URIC ACID AND ALBUMINURIA IN PATIENTS WITH TYPE 2 DIABETES. JOURNAL OF INFLAMMATORY DISEASES (THE JOURNAL OF QAZVIN UNIVERSITY OF MEDICAL SCIENCES), 12(1 (46)), 16-20. SID. https://sid.ir/paper/48818/en

Vancouver: Copy

ZIAEI AMIR, SHEYKH ALESLAMI H., SARRESHTEHDARI M., JAVADI MARYAM, KHOUEINIHA H.. ASSOCIATION OF URIC ACID AND ALBUMINURIA IN PATIENTS WITH TYPE 2 DIABETES. JOURNAL OF INFLAMMATORY DISEASES (THE JOURNAL OF QAZVIN UNIVERSITY OF MEDICAL SCIENCES)[Internet]. 2008;12(1 (46)):16-20. Available from: https://sid.ir/paper/48818/en

IEEE: Copy

AMIR ZIAEI, H. SHEYKH ALESLAMI, M. SARRESHTEHDARI, MARYAM JAVADI, and H. KHOUEINIHA, “ASSOCIATION OF URIC ACID AND ALBUMINURIA IN PATIENTS WITH TYPE 2 DIABETES,” JOURNAL OF INFLAMMATORY DISEASES (THE JOURNAL OF QAZVIN UNIVERSITY OF MEDICAL SCIENCES), vol. 12, no. 1 (46), pp. 16–20, 2008, [Online]. Available: https://sid.ir/paper/48818/en

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