DETERMINATION OF PNEUMOCOCCAL MIC TO ANTIBIOTICS IN PNEUMOCOCCUS STRAINS ISOLATED FROM ZANJAN HOSPITALS

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KARAMI AFSANEH; JOZE PANAHI M.; KARAMI A.

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Journal: Journal of Inflammatory Diseases Year:2009 | Volume:13 | Issue:2 (51) Page(s): 17-22

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Title

DETERMINATION OF PNEUMOCOCCAL MIC TO ANTIBIOTICS IN PNEUMOCOCCUS STRAINS ISOLATED FROM ZANJAN HOSPITALS

Author(s)

KARAMI AFSANEH | JOZE PANAHI M. | KARAMI A. | Issue Writer Certificate

Keywords

PNEUMONIAQ3

PENICILLINSQ3

CEFRIAXONQ3

VANCOMYCINQ3

DRUG RESISTANCEQ2

ANTIBIOTICSQ3

Abstract

Background: There are many reports associated with growing increase in incidence of DRUG RESISTANCE in streptococcus PNEUMONIAe strains, complications caused by these organisms during clinical treatment, increasing cost of therapy, and poor prognosis.Objective: To determine pneumococcus DRUG RESISTANCE in Zanjan hospitals.Methods: This was a cross-sectional study in which all positive cultures for pneumococci were collected from Bouali pulmonary center laboratory and Vali-e-Asr laboratory for determination of MIC. The data were gathered through a questionnaire and further analyzed by chi-square test using SPSS 11.5 for windows package.Findings: Of 57 patients, 25 were males and 32 females. The average age of patients was 49.4 with a range of 13-87 years. MIC test for penicillin showed that 24 (42.1%) samples were sensitive, 24 (42.1%) with intermediate susceptibility and 9 (15.8%) resistant. MIC results for ceftriaxone showed higher sensitivity among 52 samples (91/2%) and lower resistance in 5 (8/8%) specimens.All cases were sensitive to VANCOMYCIN. There was a significant relationship between underlying diseases and sensitivity to ceftriaxone.Conclusion: Regarding the high resistance of pneumococci to penicillin, it is recommended ceftriaxone to be used as the first line treatment and in case of resistance it should be replaced with VANCOMYCIN.

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APA: Copy

KARAMI, AFSANEH, JOZE PANAHI, M., & KARAMI, A.. (2009). DETERMINATION OF PNEUMOCOCCAL MIC TO ANTIBIOTICS IN PNEUMOCOCCUS STRAINS ISOLATED FROM ZANJAN HOSPITALS. JOURNAL OF INFLAMMATORY DISEASES (THE JOURNAL OF QAZVIN UNIVERSITY OF MEDICAL SCIENCES), 13(2 (51)), 17-22. SID. https://sid.ir/paper/49112/en

Vancouver: Copy

KARAMI AFSANEH, JOZE PANAHI M., KARAMI A.. DETERMINATION OF PNEUMOCOCCAL MIC TO ANTIBIOTICS IN PNEUMOCOCCUS STRAINS ISOLATED FROM ZANJAN HOSPITALS. JOURNAL OF INFLAMMATORY DISEASES (THE JOURNAL OF QAZVIN UNIVERSITY OF MEDICAL SCIENCES)[Internet]. 2009;13(2 (51)):17-22. Available from: https://sid.ir/paper/49112/en

IEEE: Copy

AFSANEH KARAMI, M. JOZE PANAHI, and A. KARAMI, “DETERMINATION OF PNEUMOCOCCAL MIC TO ANTIBIOTICS IN PNEUMOCOCCUS STRAINS ISOLATED FROM ZANJAN HOSPITALS,” JOURNAL OF INFLAMMATORY DISEASES (THE JOURNAL OF QAZVIN UNIVERSITY OF MEDICAL SCIENCES), vol. 13, no. 2 (51), pp. 17–22, 2009, [Online]. Available: https://sid.ir/paper/49112/en

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