COMPARING THE PROTEIN OF 2-HOUR AND 24-HOUR URINE SAMPLES IN PATIENTS WITH SUSPECTED PREECLAMPSIA

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HAJ SEYED JAVADI E.; ASEFZADEH S.; LAHOUTI ESHKEVARI A.S.

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Journal: Journal of Inflammatory Diseases Year:2011 | Volume:15 | Issue:2 (59) Page(s): 22-27

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Title

COMPARING THE PROTEIN OF 2-HOUR AND 24-HOUR URINE SAMPLES IN PATIENTS WITH SUSPECTED PREECLAMPSIA

Author(s)

HAJ SEYED JAVADI E. | ASEFZADEH S. | LAHOUTI ESHKEVARI A.S. | Issue Writer Certificate

Keywords

PREECLAMPSIAQ3

2-HOUR URINE PROTEINQ2

24-HOUR URINE PROTEINQ3

Abstract

Background: Determining the protein content of a 24-hour urine sample is the gold standard for diagnosis of hypertensive disorders in pregnancy.Objective: To determine whether the 2-HOUR URINE PROTEIN value can be used as a substitute for the 24-HOUR URINE PROTEIN value in patients with PREECLAMPSIA.Methods: This was a cross sectional study performed on 60 inpatient women with suspected PREECLAMPSIA due to positive urinary test strip with minimum protein content of 1+and BP³140/90 at Kosar Teaching Hospital in Qazvin (Iran) during autumn and winter 2008. Urine samples were collected within 24 hours in successive periods: The first 2-hour and the next 22-hours urine, in separate containers. The protein contents of 2-hour and 24-hour urine samples were calculated and the correlation between both groups was determined using Pearson's correlation. The cut off point for 2-HOUR URINE PROTEIN was obtained with ROC curve.Findings: Of 60 patients studied, 42 had proteinuria less then 0.3gr/24h and 18 with proteinuria higher than 0.3gr/24h. No patient with severe proteinuria (>2gr/24h) was detected. There was a significant correlation between the 2-hour and 24-HOUR URINE PROTEIN content in patients’ samples. Pearson' s correlation coefficient (r) was 0.788 (p=0.000). The cut off point for mild proteinuria was determined at 0.035gr/2h with sensitivity, specificity, positive predictive value, and negative predictive value of 63.3%, 89.5%, 77.8%, and 80.95%, respectively.Conclusion: Total protein values of 2-hour samples positively correlated with values of 24-hour samples of preeclamptic women and therefore can be substituted for assessing the protein content of 24-hour urine samples as a more convenient, faster, and cheaper method for diagnosis of PREECLAMPSIA.

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APA: Copy

HAJ SEYED JAVADI, E., ASEFZADEH, S., & LAHOUTI ESHKEVARI, A.S.. (2011). COMPARING THE PROTEIN OF 2-HOUR AND 24-HOUR URINE SAMPLES IN PATIENTS WITH SUSPECTED PREECLAMPSIA. JOURNAL OF INFLAMMATORY DISEASES (THE JOURNAL OF QAZVIN UNIVERSITY OF MEDICAL SCIENCES), 15(2 (59)), 22-27. SID. https://sid.ir/paper/49156/en

Vancouver: Copy

HAJ SEYED JAVADI E., ASEFZADEH S., LAHOUTI ESHKEVARI A.S.. COMPARING THE PROTEIN OF 2-HOUR AND 24-HOUR URINE SAMPLES IN PATIENTS WITH SUSPECTED PREECLAMPSIA. JOURNAL OF INFLAMMATORY DISEASES (THE JOURNAL OF QAZVIN UNIVERSITY OF MEDICAL SCIENCES)[Internet]. 2011;15(2 (59)):22-27. Available from: https://sid.ir/paper/49156/en

IEEE: Copy

E. HAJ SEYED JAVADI, S. ASEFZADEH, and A.S. LAHOUTI ESHKEVARI, “COMPARING THE PROTEIN OF 2-HOUR AND 24-HOUR URINE SAMPLES IN PATIENTS WITH SUSPECTED PREECLAMPSIA,” JOURNAL OF INFLAMMATORY DISEASES (THE JOURNAL OF QAZVIN UNIVERSITY OF MEDICAL SCIENCES), vol. 15, no. 2 (59), pp. 22–27, 2011, [Online]. Available: https://sid.ir/paper/49156/en

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