STUDYING THE CAUSE-EFFECT RELATION BETWEEN HELICOBACTER PYLORI AND SCC OF LARYNX AND HYPOPHARYNX.

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MOKHTARI N.; KHAJEH KARAM ALDINI M.; SAADATNIA H.; RAJATY M.

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Journal: IRANIAN JOURNAL OF OTORHINOLARYNGOLOGY Year:2004 | Volume:16 | Issue:1 (35) Page(s): 27-32

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Title

STUDYING THE CAUSE-EFFECT RELATION BETWEEN HELICOBACTER PYLORI AND SCC OF LARYNX AND HYPOPHARYNX.

Author(s)

MOKHTARI N. | KHAJEH KARAM ALDINI M. | SAADATNIA H. | RAJATY M. | Issue Writer Certificate

Keywords

LARYNX CANCERSQ3

HYPOPHARYNX CANCERSQ3

HELICOBACTER PYLORIQ2

Abstract

Objective: HELICOBACTER PYLORI has a precipitating role in the ethiopathogenesis of several benign or malignant gastrointestinal and extra- gastrointestinal diseases. The purpose of this study is determining the correlation between HELICOBACTER PYLORI and SCC of larynx and hypopharynx. Method: Serum samples of 30 patients with documented laryngeal and hypopharyngeal SCC were analyzed in search of IgG anti-H pylori using Elisa technique. Moreover, as an adjunct study we examined the presence of HELICOBACTER PYLORI in the laryngeal tumor mass using appropriate stain and specific culture medium. We did the serologic test in 30 properly matched controlswho did not have carcinoma of larynx/hypopharynx. Results: Sixty-three percent of the patient group and 26% of the control group were seropositive, which supports the role of H Pylori in the genesis of laryngeal/hypopharyngeal cancer (P<0.005, t-test). The organism was also isolated in one-third of tumoral tissues. Conclusion: HELICOBACTER PYLORI infection can be a risk factor for laryngeal/hypopharyngeal cancers in the same way as gastric cancer. This might be through a contributing effect with cigarettes and alcohol, or it may be an independent factor. More extensive studies in various communities are recommended.

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APA: Copy

MOKHTARI, N., KHAJEH KARAM ALDINI, M., SAADATNIA, H., & RAJATY, M.. (2004). STUDYING THE CAUSE-EFFECT RELATION BETWEEN HELICOBACTER PYLORI AND SCC OF LARYNX AND HYPOPHARYNX.. IRANIAN JOURNAL OF OTORHINOLARYNGOLOGY, 16(1 (35)), 27-32. SID. https://sid.ir/paper/49576/en

Vancouver: Copy

MOKHTARI N., KHAJEH KARAM ALDINI M., SAADATNIA H., RAJATY M.. STUDYING THE CAUSE-EFFECT RELATION BETWEEN HELICOBACTER PYLORI AND SCC OF LARYNX AND HYPOPHARYNX.. IRANIAN JOURNAL OF OTORHINOLARYNGOLOGY[Internet]. 2004;16(1 (35)):27-32. Available from: https://sid.ir/paper/49576/en

IEEE: Copy

N. MOKHTARI, M. KHAJEH KARAM ALDINI, H. SAADATNIA, and M. RAJATY, “STUDYING THE CAUSE-EFFECT RELATION BETWEEN HELICOBACTER PYLORI AND SCC OF LARYNX AND HYPOPHARYNX.,” IRANIAN JOURNAL OF OTORHINOLARYNGOLOGY, vol. 16, no. 1 (35), pp. 27–32, 2004, [Online]. Available: https://sid.ir/paper/49576/en

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