POISONING WITH THE NEW ANTICONVULSANT DRUGS: CLINICAL FINDINGS AND THE OUTCOME

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EIZADI MOOD NASTARAN; NADERI HOSNIEH; GHESHLAGHI FARZAD; SABZGHABAEE ALI MOHAMMAD; DANA SIADAT ZAHRA

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Journal: JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S) Year:2011 | Volume:29 | Issue:144 Page(s): 812-822

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Title

POISONING WITH THE NEW ANTICONVULSANT DRUGS: CLINICAL FINDINGS AND THE OUTCOME

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Keywords

OVERDOSEQ2

SODIUM VALPROATEQ2

LAMOTRIGINQ2

TOPIRAMATEQ2

GABAPENTINQ3

SEIZUREQ3

LOSS OF CONSCIOUSNESSQ3

INTUBATIONQ2

VENTILATIONQ2

Abstract

Background: Poisoning is one of the medical emergencies. Poisoning with new Anticonvulsant drugs such as LAMOTRIGINe, SODIUM VALPROATE, TOPIRAMATE and GABAPENTIN has been observed alone or in combination with other drugs in the last few years. Therefore this study was performed regarding the poisoning with new anticonvulsant drugs with respect to demographic, clinical manifestations, length of hospital stay, outcome and correlation between the outcome and different variables.Methods: This study was a descriptive-analytical and cross-sectional study. Simple sampling method was performed in the Noor and AliAsghar Hospital on poisoning cases with new anticonvulsant drugs. Need to INTUBATION, connected to ventilator and aspiration pneumonia were considered as outcome Statisticial analysis was done by SPSS17 using ANOVA, Student t-test and logistic regression.Findings: Poisoning with SODIUM VALPROATE was more common than LAMOTRIGINe, TOPIRAMATE and GABAPENTIN. The Mean (SD) age of study population was 27.67 (9.74) years old. The most important prediciting factors in outcome incidence were sex (male), SEIZURE, cardiovascular and respiratory symptoms in poisoning with SODIUM VALPROATE and SEIZURE in poisoning with LAMOTRIGINe. One death occurred in poisoning with SODIUM VALPROATE.Conclusion: Average age of patient was about 27.67 years which may be due to the use of these drugs in the younger age groups. The higher length of hospital stay in patients with respiratory symptoms in SODIUM VALPROATE and LAMOTRIGINe poisoning would be because of more complications (intubation, VENTILATION and aspiration penumonia) observed with these two drugs.

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APA: Copy

EIZADI MOOD, NASTARAN, NADERI, HOSNIEH, GHESHLAGHI, FARZAD, SABZGHABAEE, ALI MOHAMMAD, & DANA SIADAT, ZAHRA. (2011). POISONING WITH THE NEW ANTICONVULSANT DRUGS: CLINICAL FINDINGS AND THE OUTCOME. JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S), 29(144), 812-822. SID. https://sid.ir/paper/49898/en

Vancouver: Copy

EIZADI MOOD NASTARAN, NADERI HOSNIEH, GHESHLAGHI FARZAD, SABZGHABAEE ALI MOHAMMAD, DANA SIADAT ZAHRA. POISONING WITH THE NEW ANTICONVULSANT DRUGS: CLINICAL FINDINGS AND THE OUTCOME. JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S)[Internet]. 2011;29(144):812-822. Available from: https://sid.ir/paper/49898/en

IEEE: Copy

NASTARAN EIZADI MOOD, HOSNIEH NADERI, FARZAD GHESHLAGHI, ALI MOHAMMAD SABZGHABAEE, and ZAHRA DANA SIADAT, “POISONING WITH THE NEW ANTICONVULSANT DRUGS: CLINICAL FINDINGS AND THE OUTCOME,” JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S), vol. 29, no. 144, pp. 812–822, 2011, [Online]. Available: https://sid.ir/paper/49898/en

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