FREQUENCY OF ACCORDANCEBETWEENCELLULAR PROLIFERATION INDEX (KI67) & MICROSCOPIC TYPING OF HODGKIN'S DISEASE IN LYMPH NODE BIOPSIES

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MOKHTARI M.; SABAHI A.

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Journal: Journal of Isfahan Medical School Year:2003 | Volume:20 | Issue:67 Page(s): 86-88

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Title

FREQUENCY OF ACCORDANCEBETWEENCELLULAR PROLIFERATION INDEX (KI67) & MICROSCOPIC TYPING OF HODGKIN'S DISEASE IN LYMPH NODE BIOPSIES

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MOKHTARI M. | SABAHI A. | Issue Writer Certificate

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Abstract

Introduction: Although routine histopathologic typing of hodgkin 's disease is useful, but is not completely ideal, so a semi-quantitative index, can help the pathologist for typing in complicated cases. If proliferation index has meaningful relationship with histopathologic subtype it can by very useful for hodgkin's typing.Methods: This study was cross-sectional & analytical descriptive on 70 cases of lymph node biopsies. Sampling was simple non-incidental. From each paraffin block, two slides were prepared. One with HE staining and another with Ki67, staining. Typing of the disease and proliferation (mitotic) index 10HPF were determined.Results: Mean of proliferation index per 10HPF in lymphocytic predominance cases was 15%, in nodular sclerosis 22.6%, in mixed cellularity 27.6%, and in lymphocytic depletion was 45%.Discussion: According to variance analysis with p <0.001,F=13.5 there is a meaningful relationship between proliferation index and hodgkin's histopathologic subtype. &67 immunostaining together with HE is very useful in hodgkin's typing.

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APA: Copy

MOKHTARI, M., & SABAHI, A.. (2003). FREQUENCY OF ACCORDANCEBETWEENCELLULAR PROLIFERATION INDEX (KI67) & MICROSCOPIC TYPING OF HODGKIN'S DISEASE IN LYMPH NODE BIOPSIES. JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S), 20(67), 86-88. SID. https://sid.ir/paper/49988/en

Vancouver: Copy

MOKHTARI M., SABAHI A.. FREQUENCY OF ACCORDANCEBETWEENCELLULAR PROLIFERATION INDEX (KI67) & MICROSCOPIC TYPING OF HODGKIN'S DISEASE IN LYMPH NODE BIOPSIES. JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S)[Internet]. 2003;20(67):86-88. Available from: https://sid.ir/paper/49988/en

IEEE: Copy

M. MOKHTARI, and A. SABAHI, “FREQUENCY OF ACCORDANCEBETWEENCELLULAR PROLIFERATION INDEX (KI67) & MICROSCOPIC TYPING OF HODGKIN'S DISEASE IN LYMPH NODE BIOPSIES,” JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S), vol. 20, no. 67, pp. 86–88, 2003, [Online]. Available: https://sid.ir/paper/49988/en

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