EFFECT OF AEROBIC TRAINING AND OMEGA-3 INTAKE ON NERVE GROWTH FACTOR IN THE HIPPOCAMPUS OF HEALTHY MALE RATS AND RATS WITH HOMOCYSTEINE INDUCED ALZHEIMER'S MODEL

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

NOROUZI KAKHKI RAZIYEH; SAGHEBJOO MARZIYEH; SEGHATOLESLAMI ALI

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Journal of Isfahan Medical School Year:2016 | Volume:34 | Issue:379 Page(s): 392-400

Download Full-Text

Persian Verion

View:

1,488

Download:

Cites:

Information Journal Paper

Title

EFFECT OF AEROBIC TRAINING AND OMEGA-3 INTAKE ON NERVE GROWTH FACTOR IN THE HIPPOCAMPUS OF HEALTHY MALE RATS AND RATS WITH HOMOCYSTEINE INDUCED ALZHEIMER'S MODEL

Author(s)

NOROUZI KAKHKI RAZIYEH | SAGHEBJOO MARZIYEH | SEGHATOLESLAMI ALI | Issue Writer Certificate

Keywords

AEROBIC TRAININGQ1

OMEGA 3Q2

ALZHEIMERQ2

NERVE GROWTH FACTORQ1

Abstract

Background: The brain is organ that has high adaptability in response to morphological, metabolic and functional to exercise and nutrition. The aim of this study was to examine the effect of omega-3 intake and AEROBIC TRAINING on NERVE GROWTH FACTOR (NGF) in the hippocampus of healthy male rats and rats with homocysteine induced ALZHEIMER's model.Methods: Ninety male Wistar rats (12 weeks old and mean weight 219.99±12.60 g), were divided into 9 groups. To induce ALZHEIMER's disease, homocysteine was infused into the rats cerebroventricule at a dose of 0.6M were used. AEROBIC TRAINING on a treadmill (5 days per week, with 50 to 55% of maximal oxygen consumption) were carried out and supplemented groups during the 8 weeks, daily 800 mg per kg body weight were administered omega-3 supplements. 72 hours after the last intervention session, the rats anesthetized, and surgically removed the hippocampus tissue. Data analysis using one way ANOVA and Tukey tests were performed (P<0.05).Findings: In healthy subjects, intake of omega-3 caused a significant increase in NGF level (P=0.001). Exercise training and absence of omega-3 along with exercise training, had no significant effect on NGF levels (P=0.990 and P=0.210 respectively). In subjects with ALZHEIMER's disease, AEROBIC TRAINING caused a significant increase in NGF levels (P=0.020), and omega-3 intake with its combination with exercise training, had no significant change in the level of NGF (P=0.930 and P=0.220 respectively).Conclusion: It seems that exercise training and omega-3 intake in the strategy of prevention and treatment of ALZHEIMER's disease can affect in many different forms.

Cites

No record.

References

Cite

APA: Copy

NOROUZI KAKHKI, RAZIYEH, SAGHEBJOO, MARZIYEH, & SEGHATOLESLAMI, ALI. (2016). EFFECT OF AEROBIC TRAINING AND OMEGA-3 INTAKE ON NERVE GROWTH FACTOR IN THE HIPPOCAMPUS OF HEALTHY MALE RATS AND RATS WITH HOMOCYSTEINE INDUCED ALZHEIMER'S MODEL. JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S), 34(379), 392-400. SID. https://sid.ir/paper/50129/en

Vancouver: Copy

NOROUZI KAKHKI RAZIYEH, SAGHEBJOO MARZIYEH, SEGHATOLESLAMI ALI. EFFECT OF AEROBIC TRAINING AND OMEGA-3 INTAKE ON NERVE GROWTH FACTOR IN THE HIPPOCAMPUS OF HEALTHY MALE RATS AND RATS WITH HOMOCYSTEINE INDUCED ALZHEIMER'S MODEL. JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S)[Internet]. 2016;34(379):392-400. Available from: https://sid.ir/paper/50129/en

IEEE: Copy

RAZIYEH NOROUZI KAKHKI, MARZIYEH SAGHEBJOO, and ALI SEGHATOLESLAMI, “EFFECT OF AEROBIC TRAINING AND OMEGA-3 INTAKE ON NERVE GROWTH FACTOR IN THE HIPPOCAMPUS OF HEALTHY MALE RATS AND RATS WITH HOMOCYSTEINE INDUCED ALZHEIMER'S MODEL,” JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S), vol. 34, no. 379, pp. 392–400, 2016, [Online]. Available: https://sid.ir/paper/50129/en

Related Journal Papers