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Title

AUTOLOGOUS MELANOCYTE–KERATINOCYTE SUSPENSION IN PATIENTS WITH POSTBURN LEUKODERMA: DERMABRASION VERSUS ERBIUM YAG LASER FOR RECIPIENT SITE PREPARATION

Pages

  351-357

Abstract

 Background: PostBURN leukoderma often is associated with psychosocial disabilities in patients. Several surgical techniques are suggested for the treatment of leukodermic BURN scars. Melanocyte-keratinocyte transplant procedure (MKTP) is an important surgical modality for the treatment of this unpleasant complication. This study was designed to assess the efficacy of melanocyte-keratinocyte transplant procedure in postBURN leukoderma using DERMABRASION or ERBIUM YAG LASER for recipient site preparation.Methods: 11 patients with 44 leukoderma lesions were randomized into two groups of DERMABRASION-treated or Erbium-YAG-laser- treated recipient site for melanocyte-keratinocyte transplant procedure. Repigmentation rate and color matching were assessed at least 6 months after the treatment.Findings: The mean percentage of repigmentation in was 64.20±25.80 and 20.00±9.40 in DERMABRASION-treated and Erbium-YAG-laser treated groups, respectively (P<0.001). In DERMABRASION group, patients were significantly more satisfied than laser. No major adverse effects were observed except for hypertrophic scar and postinflammatory hyperpigmentation in 2 patients at the donor and recipient sites, respectively.Conclusion: Transplantation of autologous melanocyte-keratinocyte suspension could be considered as an effective and potentially safe treatment in leukodermic BURN scars. Better results were achieved with DERMABRASION for de-epithelialization of the recipient sites compared to ERBIUM YAG LASER. Further studies on larger series of patients are needed to confirm the efficacy of melanocyte-keratinocyte transplant procedure in treating postBURN leukoderma.

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    APA: Copy

    JAFFARY, FARIBA, MOKHTARI, FATEMEH, MATIN, MARZIEH, & NILFOROUSHZADEH, MOHAMMAD ALI. (2017). AUTOLOGOUS MELANOCYTE–KERATINOCYTE SUSPENSION IN PATIENTS WITH POSTBURN LEUKODERMA: DERMABRASION VERSUS ERBIUM YAG LASER FOR RECIPIENT SITE PREPARATION. JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S), 35(424), 351-357. SID. https://sid.ir/paper/50300/en

    Vancouver: Copy

    JAFFARY FARIBA, MOKHTARI FATEMEH, MATIN MARZIEH, NILFOROUSHZADEH MOHAMMAD ALI. AUTOLOGOUS MELANOCYTE–KERATINOCYTE SUSPENSION IN PATIENTS WITH POSTBURN LEUKODERMA: DERMABRASION VERSUS ERBIUM YAG LASER FOR RECIPIENT SITE PREPARATION. JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S)[Internet]. 2017;35(424):351-357. Available from: https://sid.ir/paper/50300/en

    IEEE: Copy

    FARIBA JAFFARY, FATEMEH MOKHTARI, MARZIEH MATIN, and MOHAMMAD ALI NILFOROUSHZADEH, “AUTOLOGOUS MELANOCYTE–KERATINOCYTE SUSPENSION IN PATIENTS WITH POSTBURN LEUKODERMA: DERMABRASION VERSUS ERBIUM YAG LASER FOR RECIPIENT SITE PREPARATION,” JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S), vol. 35, no. 424, pp. 351–357, 2017, [Online]. Available: https://sid.ir/paper/50300/en

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