RELATIONSHIP BETWEEN SERUM CAFFEINE AND PREECLAMPSIA IN PREGNANT WOMEN

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DOOZANDEH ZIBA; KESHAVARZ TAHEREH; TAVANA ZOHREH; MOSHFEGH ZINAB; SAYADI MEHRAB

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Journal: JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S) Year:2011 | Volume:29 | Issue:156 Page(s): 1288-1295

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Title

RELATIONSHIP BETWEEN SERUM CAFFEINE AND PREECLAMPSIA IN PREGNANT WOMEN

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Keywords

CAFFEINEQ2

PREECLAMPSIAQ3

PREGNANCYQ2

Abstract

Background: PREECLAMPSIA is a vascular disease that happens during PREGNANCY. It is created by vasospasm and vascular endothelium activity and is one of the most important complications of PREGNANCY.Blood pressure disorders in PREGNANCY are one of the three major reasons of mothers’ mortality. The aim of this study was to determine the relation between serum CAFFEINE and PREECLAMPSIA in PREGNANCY.Methods: This was a case-control study.44 pregnant women in Shiraz, Iran, aged 18-35 years, were enrolled in the study. Based on the criteria of entering, 22 women with PREECLAMPSIA and 22 women with normal blood pressure were selected by systematic random sampling from women reffered to 2 hospitals in Shiraz. Initially, demographic data and daily CAFFEINE intake was gathered. Then, serum CAFFEINE level was measured for all of the subjects. The data was analyzed by Student t-test and multivariate logistic regression.Findings: The mean amount of serum CAFFEINE was 0.309 ± 0.292 and 0.468 ± 0.314 in case and control group, respectively (P=0.094). Logestic regression analysis did not show a significant correlation between serum CAFFEINE levels and PREECLAMPSIA (OR=0.565, 95% CI: 0.013-25.42). The correlation between maternal age (OR=1.52, 95% CI: 1.08- 2.15) and gestational age (OR=1.43, 95% CI: 1.09-1.87) with PREECLAMPSIA were significant.Conclusion: There is no significance relationship between PREECLAMPSIA and the CAFFEINE level of the serum based on our findings. Therefore, restricting the CAFFEINE consumption in pregnant women does not seem rational.

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APA: Copy

DOOZANDEH, ZIBA, KESHAVARZ, TAHEREH, TAVANA, ZOHREH, MOSHFEGH, ZINAB, & SAYADI, MEHRAB. (2011). RELATIONSHIP BETWEEN SERUM CAFFEINE AND PREECLAMPSIA IN PREGNANT WOMEN. JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S), 29(156), 1288-1295. SID. https://sid.ir/paper/50572/en

Vancouver: Copy

DOOZANDEH ZIBA, KESHAVARZ TAHEREH, TAVANA ZOHREH, MOSHFEGH ZINAB, SAYADI MEHRAB. RELATIONSHIP BETWEEN SERUM CAFFEINE AND PREECLAMPSIA IN PREGNANT WOMEN. JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S)[Internet]. 2011;29(156):1288-1295. Available from: https://sid.ir/paper/50572/en

IEEE: Copy

ZIBA DOOZANDEH, TAHEREH KESHAVARZ, ZOHREH TAVANA, ZINAB MOSHFEGH, and MEHRAB SAYADI, “RELATIONSHIP BETWEEN SERUM CAFFEINE AND PREECLAMPSIA IN PREGNANT WOMEN,” JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S), vol. 29, no. 156, pp. 1288–1295, 2011, [Online]. Available: https://sid.ir/paper/50572/en

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