LEUKOCYTOSIS AND HEART FAILURE IN ACUTE MYOCARDIAL INFARCTION

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ESKANDARIAN R.; GHORBANI RAHEB; MALEK MOJTABA; ASGARI ZAHRA; DARABIAN MOHSEN; ZAHMATKESH M.

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Journal: Journal of Isfahan Medical School Year:2007 | Volume:25 | Issue:86 Page(s): 62-69

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Title

LEUKOCYTOSIS AND HEART FAILURE IN ACUTE MYOCARDIAL INFARCTION

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Keywords

LEUKOCYTOSISQ2

NEUTROPHILIAQ3

MONOCYTOSISQ3

MYOCARDIAL INFARCTIONQ2

HEART FAILUREQ3

Abstract

Background: Mortality of MYOCARDIAL INFARCTION (MI) may due to arrhythmia or pump failure. LEUKOCYTOSIS especially NEUTROPHILIA is a feature of inflammatory response. This study was performed to evaluate the association between LEUKOCYTOSIS at time of admission and further HEART FAILURE after the acute MI.Methods: This case-control study performed among patients with acute MI. In patients referred to the hospital during first 24 hours of chest pain, blood sample was achieved for measuring cardiac enzymes and blood cell count. Echocardiography was performed after 3-5 days. A number of 69 patients with ejection fraction<45% underwent HEART FAILURE (case group) and 69 matched patients with ejection fraction³45% (control group) were checked for major cardiac risk factors, as well as for sex.Findings: LEUKOCYTOSIS (WBC³11000) was observed in 47.8% and 20.3% of patients in case and control groups, respectively (p=0.001). NEUTROPHILIA (neutrophil>65%) was observed in 69.6% and 34.8% of patients in case and control groups, respectively (p<0.0001). There was significant relationship between LEUKOCYTOSIS and NEUTROPHILIA and future HEART FAILURE. MONOCYTOSIS (monocyte>2%) was seen in 33.3% and 40.6% of patients in case and control groups, respectively (p=0.3).Conclusion: LEUKOCYTOSIS and NEUTROPHILIA can be considered as predicting factors for HEART FAILURE in acute phase of MI and it can be used for determining the risk of HEART FAILURE in those patients.

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APA: Copy

ESKANDARIAN, R., GHORBANI, RAHEB, MALEK, MOJTABA, ASGARI, ZAHRA, DARABIAN, MOHSEN, & ZAHMATKESH, M.. (2007). LEUKOCYTOSIS AND HEART FAILURE IN ACUTE MYOCARDIAL INFARCTION. JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S), 25(86), 62-69. SID. https://sid.ir/paper/50810/en

Vancouver: Copy

ESKANDARIAN R., GHORBANI RAHEB, MALEK MOJTABA, ASGARI ZAHRA, DARABIAN MOHSEN, ZAHMATKESH M.. LEUKOCYTOSIS AND HEART FAILURE IN ACUTE MYOCARDIAL INFARCTION. JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S)[Internet]. 2007;25(86):62-69. Available from: https://sid.ir/paper/50810/en

IEEE: Copy

R. ESKANDARIAN, RAHEB GHORBANI, MOJTABA MALEK, ZAHRA ASGARI, MOHSEN DARABIAN, and M. ZAHMATKESH, “LEUKOCYTOSIS AND HEART FAILURE IN ACUTE MYOCARDIAL INFARCTION,” JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S), vol. 25, no. 86, pp. 62–69, 2007, [Online]. Available: https://sid.ir/paper/50810/en

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