CENTRAL NERVOUS SYSTEM BLEEDING IN FACTOR XIII DEFICIENCY, ASSESSMENT THE ROLE OF PLASMINOGEN ACTIVATOR INHIBITOR-1

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

NADERI MAJID; DORGALALEH AKBAR; SHABAN ALIZADEH; KAZEMI AHMAD; TABIBIAN SHADI; GHUTASLOU ABBAS; KASHIRI MEYSAM; HOSSEINI HOSNIEH; HOSSEINI MARYAM AL SADAT

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S) Year:2014 | Volume:31 | Issue:263 Page(s): 1985-1993

Download Full-Text

Persian Verion

View:

1,223

Download:

Cites:

Information Journal Paper

Title

CENTRAL NERVOUS SYSTEM BLEEDING IN FACTOR XIII DEFICIENCY, ASSESSMENT THE ROLE OF PLASMINOGEN ACTIVATOR INHIBITOR-1

Author(s)

Keywords

F13 DEFICIENCYQ2

CENTRAL NERVOUS SYSTEM (CNS) BLEEDINGQ2

INTRACRANIAL HEMORRHAGEQ2

EXTRACRANIAL HEMORRHAGEQ2

Abstract

Background: Factor XIII deficiency is a rare bleeding disorder (RBD) with a high incidence in Sistan and Baluchistan province, Iran. Central nervous system (CNS) bleeding is a common but lifethreatening clinical presentation of severe factor XIII deficiency. This study aimed to assess the role of PAI-14G/5G polymorphism in occurrence of intra and EXTRACRANIAL HEMORRHAGE in factor 13 deficiency.Methods: In this study, 64 patient with factor XIII deficiency were enrolled. Initially, according to the history of occurrence of CNS bleeding, patients were divided in two groups of case and control. At the baseline, both groups were evaluated for the Trp187Arg polymorphism in order to confirm their disorder. Then, all patients were assessed for PAI-14G/5G polymorphism.Findings: All study patients were homozygote for factor XIII polymorphism. We also found that the equal numbers of patients (4 individuals) in case and control groups were heterozygote for PAI-14G/5G polymorphism and none of patients were homozygote for this polymorphism. All heterozygote patients had INTRACRANIAL HEMORRHAGE and patients with EXTRACRANIAL HEMORRHAGE had no mutation of PAI-14G/5G.Conclusion: PAI-14G/5G polymorphism did not any effect on occurrence of intra and EXTRACRANIAL HEMORRHAGE in patients with factor 13 deficiency.

Cites

No record.

References

No record.

Cite

APA: Copy

NADERI, MAJID, DORGALALEH, AKBAR, SHABAN, ALIZADEH, KAZEMI, AHMAD, TABIBIAN, SHADI, GHUTASLOU, ABBAS, KASHIRI, MEYSAM, HOSSEINI, HOSNIEH, & HOSSEINI, MARYAM AL SADAT. (2014). CENTRAL NERVOUS SYSTEM BLEEDING IN FACTOR XIII DEFICIENCY, ASSESSMENT THE ROLE OF PLASMINOGEN ACTIVATOR INHIBITOR-1. JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S), 31(263), 1985-1993. SID. https://sid.ir/paper/50874/en

Vancouver: Copy

NADERI MAJID, DORGALALEH AKBAR, SHABAN ALIZADEH, KAZEMI AHMAD, TABIBIAN SHADI, GHUTASLOU ABBAS, KASHIRI MEYSAM, HOSSEINI HOSNIEH, HOSSEINI MARYAM AL SADAT. CENTRAL NERVOUS SYSTEM BLEEDING IN FACTOR XIII DEFICIENCY, ASSESSMENT THE ROLE OF PLASMINOGEN ACTIVATOR INHIBITOR-1. JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S)[Internet]. 2014;31(263):1985-1993. Available from: https://sid.ir/paper/50874/en

IEEE: Copy

MAJID NADERI, AKBAR DORGALALEH, ALIZADEH SHABAN, AHMAD KAZEMI, SHADI TABIBIAN, ABBAS GHUTASLOU, MEYSAM KASHIRI, HOSNIEH HOSSEINI, and MARYAM AL SADAT HOSSEINI, “CENTRAL NERVOUS SYSTEM BLEEDING IN FACTOR XIII DEFICIENCY, ASSESSMENT THE ROLE OF PLASMINOGEN ACTIVATOR INHIBITOR-1,” JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S), vol. 31, no. 263, pp. 1985–1993, 2014, [Online]. Available: https://sid.ir/paper/50874/en

Related Journal Papers