THE EFFECT OF INSULIN ON ELECTERICAL ACTIVITY IN THE RAT

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SHARIFI M.R.; ALAEI H.; RAEISI P.

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

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Journal: Journal of Isfahan Medical School Year:2005 | Volume:23 | Issue:79 Page(s): 56-62

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Information Journal Paper

Title

THE EFFECT OF INSULIN ON ELECTERICAL ACTIVITY IN THE RAT

Author(s)

SHARIFI M.R. | ALAEI H. | RAEISI P. | Issue Writer Certificate

Keywords

INSULINQ2

ELECTROENCEPHALOGRAPHYQ4

BRAINQ2

RATQ3

BRAIN WAVESQ4

Abstract

Introduction: INSULIN has profound effects on the central nervous system (CNS), in so far as some neurodegenerative diseases have been related to INSULIN. In this study, we evaluated the effect of INSULIN on the electrical activity of BRAIN (EEG) in RAT.Methods: Thirty male RATs were used in this study. The RATs were divided into 3 groups. Groups 1, 2 and 3 received INSULIN at doses of 0.1µg/kg, 1µg/kg, and 2µg/kg, respectively. After receiving INSULIN intraperitoneally, the animals underwent ELECTROENCEPHALOGRAPHY.Results: The results showed that a low dose of INSULIN increased delta waves of EEG and decreased alpha, beta and theta waves.Discussion: The results demonstrate that low-dose INSULIN decreased BRAIN activity. High-dose INSULIN led to reduction of delta wave in EEG and increased alpha, theta and especially beta waves. These results demonstrate the elevation of BRAIN activity which may have been due to penetration of the BBB by INSULIN and its likely direct effect on the CNS.

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APA: Copy

SHARIFI, M.R., ALAEI, H., & RAEISI, P.. (2005). THE EFFECT OF INSULIN ON ELECTERICAL ACTIVITY IN THE RAT. JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S), 23(79), 56-62. SID. https://sid.ir/paper/50919/en

Vancouver: Copy

SHARIFI M.R., ALAEI H., RAEISI P.. THE EFFECT OF INSULIN ON ELECTERICAL ACTIVITY IN THE RAT. JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S)[Internet]. 2005;23(79):56-62. Available from: https://sid.ir/paper/50919/en

IEEE: Copy

M.R. SHARIFI, H. ALAEI, and P. RAEISI, “THE EFFECT OF INSULIN ON ELECTERICAL ACTIVITY IN THE RAT,” JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S), vol. 23, no. 79, pp. 56–62, 2005, [Online]. Available: https://sid.ir/paper/50919/en

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