UBD IDENTIFY IN PARAFFIN TISSUES IN PATIENTS WITH COLORECTAL CANCER

Q: How can I download an article?

To download an article from SID, first log in to the site, search for the article title, and click on the 'Download Article' option.

Q: How can I download an ISI article?

To download an ISI article on SID, enter the keyword or article title in the search bar, view the relevant results, click on the desired article, and select the 'Download Article' option.

Q: How can I access the SID database?

To access the SID database, visit SID.ir, create an account, and log in to access scientific resources.

Q: Is downloading articles from SID free?

Some articles on SID are available for free, while others require payment. Details are specified on the article's page.

IZADI AMIR; MOSLEMI ELHAM; POORHOSSEINI SEYED MOHAMMAD; YASSAEE VAHID REZA; KHEIRI HAMID REZA; ELIKAI HAMID REZA

مرکز اطلاعات علمی Scientific Information Database (SID) - Trusted Source for Research and Academic Resources

Journal Paper

Paper Information

Journal: Journal of Isfahan Medical School Year:2014 | Volume:32 | Issue:291 Page(s): 1-10

Download Full-Text

Persian Verion

View:

960

Download:

Cites:

Information Journal Paper

Title

UBD IDENTIFY IN PARAFFIN TISSUES IN PATIENTS WITH COLORECTAL CANCER

Author(s)

Keywords

UBDQ2

COLORECTAL CANCERQ2

RT-PCRQ2

Abstract

Background: Colon cancer is one major cause for cancer-related deaths. UBD and its alike proteins are signal transduction pathways with several cellular functions including and DNA repair control. There is relation between increase in UBD and increase in p53 expression in a way that in many cases this growth has accelerated the cancer progress. The aims of this study are to detect UBD as a marker for the early detection of COLORECTAL CANCER and disease progress in patients.Methods: 30 samples of paraffin tissue blocks of COLORECTAL CANCER patients and 10 normal tissue samples, the selected slices were collected. RT-PCR testing to detect UBD gene and b-actin gene as an internal control were obtained.Findings: The size of RT-PCR product of UBD gene was 395 base pair and the size of amplified bactin was 350bp. The RT-PCR of b-actin was positive in all samples. The RT-PCR products of 18 samples (95%) of male patients and 11 samples (100%) of female patients were positive. Only one sample had negative product.Conclusion: Considering the results we can conclude that UBD as a useful marker that is independent of tumor stage plays an important role in the detection of COLORECTAL CANCER and it’s study is really important in identification and detection of early stages of disease. Results showed that the expression of the UBD in patients is 97% and it reduces to 5% in healthy people.

Cites

References

No record.

Cite

APA: Copy

IZADI, AMIR, MOSLEMI, ELHAM, POORHOSSEINI, SEYED MOHAMMAD, YASSAEE, VAHID REZA, KHEIRI, HAMID REZA, & ELIKAI, HAMID REZA. (2014). UBD IDENTIFY IN PARAFFIN TISSUES IN PATIENTS WITH COLORECTAL CANCER. JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S), 32(291), 1-10. SID. https://sid.ir/paper/51126/en

Vancouver: Copy

IZADI AMIR, MOSLEMI ELHAM, POORHOSSEINI SEYED MOHAMMAD, YASSAEE VAHID REZA, KHEIRI HAMID REZA, ELIKAI HAMID REZA. UBD IDENTIFY IN PARAFFIN TISSUES IN PATIENTS WITH COLORECTAL CANCER. JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S)[Internet]. 2014;32(291):1-10. Available from: https://sid.ir/paper/51126/en

IEEE: Copy

AMIR IZADI, ELHAM MOSLEMI, SEYED MOHAMMAD POORHOSSEINI, VAHID REZA YASSAEE, HAMID REZA KHEIRI, and HAMID REZA ELIKAI, “UBD IDENTIFY IN PARAFFIN TISSUES IN PATIENTS WITH COLORECTAL CANCER,” JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S), vol. 32, no. 291, pp. 1–10, 2014, [Online]. Available: https://sid.ir/paper/51126/en

Related Journal Papers