EVALUATING THE PROPHYLACTIC EFFECT OF MAGNESIUM SULFATE AND COMBINATION OF MIDAZOLAM AND KETAMINE FOR PREVENTION OF SHIVERING DURING REGIONAL ANAESTHESIA

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HONARMAND AZIM; SAFAVI MOHAMMAD REZA; MANSORIAN SIMIN

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Paper Information

Journal: Journal of Isfahan Medical School Year:2016 | Volume:34 | Issue:399 Page(s): 1097-1105

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Title

EVALUATING THE PROPHYLACTIC EFFECT OF MAGNESIUM SULFATE AND COMBINATION OF MIDAZOLAM AND KETAMINE FOR PREVENTION OF SHIVERING DURING REGIONAL ANAESTHESIA

Author(s)

HONARMAND AZIM | SAFAVI MOHAMMAD REZA | MANSORIAN SIMIN | Issue Writer Certificate

Keywords

SHIVERINGQ3

SPINAL ANAESTHESIAQ2

MAGNESIUM SULFATEQ1

MIDAZOLAMQ3

KETAMINEQ2

Abstract

Background: SHIVERING after SPINAL ANAESTHESIA is an unpleasant feeling that causes discomfort for patient and interferes with monitoring systems. The goal of this study was comparing the prophylactic use of MAGNESIUM SULFATE infusion and MIDAZOLAM plus KETAMINE for prevention of SHIVERING in SPINAL ANAESTHESIA.Methods: In this double-blinded study, 90 patients with status 1 or 2 of American Society of Anesthesiologists (ASA) classification, undergoing orthopedic surgery under SPINAL ANAESTHESIA (with 15 mg of bupivacaine), were included. All the patients were randomly allocated to one of three equal groups: 1) Group MK received 0.25 mg KETAMINE+37.5 µg/kg MIDAZOLAM. 2) Group Mg received intravenous (IV) bolus dose of 80 mg/kg MgSO4 over 30 minute period followed by infusion of 2 g/hour. Group S received saline without any prophylactic drug. SHIVERING score was recorded at 10-minutes intervals. Peripheral and core body temperature were recorded at -10 minutes intervals.Findings: SHIVERING frequency and intensity were significantly higher in group S compared to groups MK (P=0.001) and Mg (P<0.001); but there was no significant difference between groups MK and Mg (P=0.232) for frequency, and P=0.248 for intensity). Receiving pethidine to control SHIVERING was significantly higher in group S compared to proup MK and Mg (P<0.001 for both); but there was no significant difference between groups MK and Mg (P>0.999).Conclusion: There was no difference between the use of KETAMINE plus MIDAZOLAM and MAGNESIUM SULFATE in preventing SHIVERING during SPINAL ANAESTHESIA.

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References

EFFECTS OF MAGNESIUM SULFATE ON PREVENTION OF SHIVERING DURING SPINAL ANESTHESIA IN CESAREAN SECTION

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APA: Copy

HONARMAND, AZIM, SAFAVI, MOHAMMAD REZA, & MANSORIAN, SIMIN. (2016). EVALUATING THE PROPHYLACTIC EFFECT OF MAGNESIUM SULFATE AND COMBINATION OF MIDAZOLAM AND KETAMINE FOR PREVENTION OF SHIVERING DURING REGIONAL ANAESTHESIA. JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S), 34(399), 1097-1105. SID. https://sid.ir/paper/51128/en

Vancouver: Copy

HONARMAND AZIM, SAFAVI MOHAMMAD REZA, MANSORIAN SIMIN. EVALUATING THE PROPHYLACTIC EFFECT OF MAGNESIUM SULFATE AND COMBINATION OF MIDAZOLAM AND KETAMINE FOR PREVENTION OF SHIVERING DURING REGIONAL ANAESTHESIA. JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S)[Internet]. 2016;34(399):1097-1105. Available from: https://sid.ir/paper/51128/en

IEEE: Copy

AZIM HONARMAND, MOHAMMAD REZA SAFAVI, and SIMIN MANSORIAN, “EVALUATING THE PROPHYLACTIC EFFECT OF MAGNESIUM SULFATE AND COMBINATION OF MIDAZOLAM AND KETAMINE FOR PREVENTION OF SHIVERING DURING REGIONAL ANAESTHESIA,” JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S), vol. 34, no. 399, pp. 1097–1105, 2016, [Online]. Available: https://sid.ir/paper/51128/en

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