BOOSTER PHENOMENON OF 3-STEP TUBERCULIN SKIN TESTING IN HEMODIALYSIS PATIENTS

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MEIDANI MOHSEN; MORTAZAVI NAJAFABADI MOZHGAN; EMAMI NAEINI ALIREZA; KHORVASH FARZIN; REZAEE NEDA

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Journal: JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S) Year:2011 | Volume:28 | Issue:116 Page(s): 1049-1055

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Title

BOOSTER PHENOMENON OF 3-STEP TUBERCULIN SKIN TESTING IN HEMODIALYSIS PATIENTS

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Keywords

HEMODIALYSISQ3

BOOSTER EFFECTQ3

TUBERCULIN SKIN TESTQ2

TUBERCULOSISQ3

Abstract

Background: The risk of increasing active TUBERCULOSIS is a significant health problem among patients receiving HEMODIALYSIS. Also prophylactic therapy against TUBERCULOSIS in these patients is important to have a successful transplantation. The TUBERCULIN SKIN TEST (TST) is used to detect TUBERCULOSIS infection, but uremia in these patients may lead to coetaneous anergy that decrease the accuracy of the test. The aim of study was to identify the TST reactivity and frequency of booster phenomenon in 3-step TST in under HEMODIALYSIS patients.Methods: A total of 74 patients in Alzahra and Zahraye Marziye HEMODIALYSIS center in Isfahan were prospectively tested. To determine the frequency of BOOSTER EFFECT, patients with less than 10 mm indurations were given additional TST one and four weeks after the initial test.Finding: Totally, 12 (16.2%) of 74 patients showed a positive tuberculin reaction (³ 10 mm) on the initial test. Positive TST in 8 patients (10.8%) was added after the second test and in 6 patients (8.1%) after the third test. The booster phenomenon was detected in 24% of the patients. There was a significant correlation between TST positivity and anemia. There was no influence of age, gender, serum albumin level, urea reduction ratio and KT/V (P>0.05).Conclusion: According to the results and the necessity of diagnosis of latent tubercosis in HEMODIALYSIS patients, our study support 3-step TUBERCULIN SKIN TESTing in HEMODIALYSIS patients. As TST is easy and inexpensive, it seems to be useful for kidney transplant candidates.

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APA: Copy

MEIDANI, MOHSEN, MORTAZAVI NAJAFABADI, MOZHGAN, EMAMI NAEINI, ALIREZA, KHORVASH, FARZIN, & REZAEE, NEDA. (2011). BOOSTER PHENOMENON OF 3-STEP TUBERCULIN SKIN TESTING IN HEMODIALYSIS PATIENTS. JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S), 28(116), 1049-1055. SID. https://sid.ir/paper/51185/en

Vancouver: Copy

MEIDANI MOHSEN, MORTAZAVI NAJAFABADI MOZHGAN, EMAMI NAEINI ALIREZA, KHORVASH FARZIN, REZAEE NEDA. BOOSTER PHENOMENON OF 3-STEP TUBERCULIN SKIN TESTING IN HEMODIALYSIS PATIENTS. JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S)[Internet]. 2011;28(116):1049-1055. Available from: https://sid.ir/paper/51185/en

IEEE: Copy

MOHSEN MEIDANI, MOZHGAN MORTAZAVI NAJAFABADI, ALIREZA EMAMI NAEINI, FARZIN KHORVASH, and NEDA REZAEE, “BOOSTER PHENOMENON OF 3-STEP TUBERCULIN SKIN TESTING IN HEMODIALYSIS PATIENTS,” JOURNAL OF ISFAHAN MEDICAL SCHOOL (I.U.M.S), vol. 28, no. 116, pp. 1049–1055, 2011, [Online]. Available: https://sid.ir/paper/51185/en

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