COMPARISON OF DEXAMETHAZONE AND ONDANSETRON WITH DEXAMETHAZONE AND METOCLOPRAMIDEIN PREVENTATION OF POST – OPERATIVE NAUSEA AND VOMITING

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SAHABI S.M.; ALE REZA H.; ALIJANPOUR E.; BANIHASHEM N.; HASANNASAB B.; SEYFI SAFOURA

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Journal: MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES Year:2010 | Volume:53 | Issue:2 Page(s): 73-78

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Title

COMPARISON OF DEXAMETHAZONE AND ONDANSETRON WITH DEXAMETHAZONE AND METOCLOPRAMIDEIN PREVENTATION OF POST – OPERATIVE NAUSEA AND VOMITING

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HYSTERECTOMYQ3

NAUSEAQ2

ONDANSETRON METOCLOPRAMIDEQ3

VOMITINGQ3

Abstract

Introduction: Positive effectiveness of antiemetic drugs was approved in reduction of post-operative NAUSEAand VOMITING) PONV. The purpose of this study was comparison of Dexamethazone and Ondansetron with Dexamethazone and Metoclopramide in preventation of PONV.Materials and Methods: In this study, was selected 80 women in ASA class I, II for elective abdominal HYSTERECTOMY under general anaesthesia and was divided in to two groups (n= 40). One group received a combination of Dexamethazone with Ondansetron and in second group was injected a combination of Dexamethasone with Metoclopramide near the end of surgery. PONV was evaluated at 2hr and 6 hr after operation. The results were analyzed, using pearson chi-square and fisher’s exact test.Results: Injection of two drugs Ondansetron and Metoclopramide affect in reduction PONV. But, the rate of reduction of NAUSEA and VOMITING was not significant in 2 groups in 2 hr after surgery (p= 0.723). Its rate was significantly lower in Ondansetron group after 6 hr (p< 0/001).Conclusion: In the patients with selective HYSTERECTOMY under general anesthesia for reduction of PONV can be apply from acombination of Dexamethasone and Ondansetron which show more effectiveness and longer duration as compared to Metoclopramide and Dexamethasone.

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APA: Copy

SAHABI, S.M., ALE REZA, H., ALIJANPOUR, E., BANIHASHEM, N., HASANNASAB, B., & SEYFI, SAFOURA. (2010). COMPARISON OF DEXAMETHAZONE AND ONDANSETRON WITH DEXAMETHAZONE AND METOCLOPRAMIDEIN PREVENTATION OF POST – OPERATIVE NAUSEA AND VOMITING. MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES, 53(2), 73-78. SID. https://sid.ir/paper/51374/en

Vancouver: Copy

SAHABI S.M., ALE REZA H., ALIJANPOUR E., BANIHASHEM N., HASANNASAB B., SEYFI SAFOURA. COMPARISON OF DEXAMETHAZONE AND ONDANSETRON WITH DEXAMETHAZONE AND METOCLOPRAMIDEIN PREVENTATION OF POST – OPERATIVE NAUSEA AND VOMITING. MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2010;53(2):73-78. Available from: https://sid.ir/paper/51374/en

IEEE: Copy

S.M. SAHABI, H. ALE REZA, E. ALIJANPOUR, N. BANIHASHEM, B. HASANNASAB, and SAFOURA SEYFI, “COMPARISON OF DEXAMETHAZONE AND ONDANSETRON WITH DEXAMETHAZONE AND METOCLOPRAMIDEIN PREVENTATION OF POST – OPERATIVE NAUSEA AND VOMITING,” MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES, vol. 53, no. 2, pp. 73–78, 2010, [Online]. Available: https://sid.ir/paper/51374/en

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