SEROEPIDEMIOLOGY OF HTLV-1 IN NEISHABOUR

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FARID HOSSINI R.; GHAFARI JAVAD; MIRI S.; NASIRIAN A.; RAFATPANAH H.

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Journal: MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES Year:2005 | Volume:47 | Issue:86 Page(s): 417-424

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Title

SEROEPIDEMIOLOGY OF HTLV-1 IN NEISHABOUR

Author(s)

Keywords

HTLV-I INFECTIONQ4

SEROPREVALENCE OF HTLV-IQ4

HTLV-I- ASSOCIATED MYELOPATHY TROPICAL SPASTIC PARAPARESIS AND ADULT T- CELLLEUKEMIAQ4

Abstract

Introduction: Human T cell Lymphotropic Virus Type 1 (HTLV-I) infection has been recognized as the causative agents of two diseases; HTLV-1- associated myelopathy tropical spastic paraparesis (HAMITSP) and adult T- cell leukemia (ATL). Approximately 15- 20 millions people are infected with HTLV-I all over the world. The North- East Iran (Mashhad) has been considered as a new endemic area for HTLV- I infection especially Neishaboor. The purpose of this study was the seroepidemiologic study of HTLV-1 in Neishaboor.Materials and Methods: This cross-sectional study was done in Neishaboor in 2002. Neishaboor (without rural areas) is divided into 5 health sections. A total number of 1003 subjects were selected randomly proportional to the population of each region. 5cc of venous blood was obtained from cach subject and assessed serologically by Eliza method at immunology laboratory of Ghaem hospital. A questioner was provided for data collection of each person. The collected data was analyzed with using of T, Mann Whitney and regression tests.Results: 1- The seroprevalence of HTLV-I INFECTION was 3.4% in Neishaboor (95% CI= 2.3- 4.5%).2- Male/female ratio was 33/67 in serum positive population.3- HTLV-I INFECTION was increased with age.4- As expected, the prevalence of infection did not show a uniform distribution throughout the city: a. The most ancient part (region 2) of the city had the highest prevalence (4.9%). b. The rate of infection was more prevalent in the center of city (region 1, 2) in comparison with the peripheral regions of the city (regions 3, 4).5- The main risk factors for acquisition of HTLV-I INFECTION are breast feeding, blood transfusion, surgery and sexual transmission.Conclusion: Our results strongly suggest that screening of blood bank donors for HTLV-I INFECTION and limiting of other routes of HTLV-I transmission such as breast feeding, surgery and sexual transmission should be considered to prevent of HTLV-I INFECTION in Neishaboor and other endemic areas.

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THE EVALUATION OF PERIODONTIUM IN PATIENT'S WITH SPASTIC PARAPARESEIS RELATED TO HTLVI VIRUS

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APA: Copy

FARID HOSSINI, R., GHAFARI, JAVAD, MIRI, S., NASIRIAN, A., & RAFATPANAH, H.. (2005). SEROEPIDEMIOLOGY OF HTLV-1 IN NEISHABOUR. MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES, 47(86), 417-424. SID. https://sid.ir/paper/51681/en

Vancouver: Copy

FARID HOSSINI R., GHAFARI JAVAD, MIRI S., NASIRIAN A., RAFATPANAH H.. SEROEPIDEMIOLOGY OF HTLV-1 IN NEISHABOUR. MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2005;47(86):417-424. Available from: https://sid.ir/paper/51681/en

IEEE: Copy

R. FARID HOSSINI, JAVAD GHAFARI, S. MIRI, A. NASIRIAN, and H. RAFATPANAH, “SEROEPIDEMIOLOGY OF HTLV-1 IN NEISHABOUR,” MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES, vol. 47, no. 86, pp. 417–424, 2005, [Online]. Available: https://sid.ir/paper/51681/en

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