HISTOLOGIC EVALUATION OF 120 INFERTILE TESTICULAR BIOPSY

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KHOEI A.; TAFAZOLI M.

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Journal: Medical Journal of Mashhad University of Medical Sciences Year:2005 | Volume:47 | Issue:86 Page(s): 373-382

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Title

HISTOLOGIC EVALUATION OF 120 INFERTILE TESTICULAR BIOPSY

Author(s)

KHOEI A. | TAFAZOLI M. | Issue Writer Certificate

Keywords

INFERTILITYQ2

GERM CELL APLASIA (G.C.A) OR SERTOLI CELL ONLY SYNDROMQ4

MATURATION ARREST HYPOSPERMATOGENESISQ4

TESTICULAR ATROPHYQ4

TESTICULAR PATHOLOGYQ4

TESTICULAR BIOPSYQ4

Abstract

Introduction: TESTICULAR BIOPSY is an useful method in INFERTILITY diagnosis and predicting prognosis, especially m patients With azosperrma and normal level of serum FSH that primary evaluating procedures can't differentiate spermatogenesis defect from obstructive one. If the etiology of INFERTILITY is an obstructive lesion the prognosis is often good and usually curable, by surgery. The purpose of this study was to evauate various histopathologic changes in incisional testicular biopsies of the infertile men in order to predict frequency of different tissue morphologies and especially interpreter these histopathologic changes for better understanding the diverse etiology of INFERTILITY.Material and method: In this clinicolaboratory study performed in Anatomic pathology department of mashhad Emam Reza hospital, Testicular biopsies of 120 Infertile men were histopathologically reevaluated and reclassified applying newly introduced criteria.Clinical data such as age, disease history, associated disorders and results of spermogram were gathered in designed forms. Final data were processed by descriptive statistical method and frequency distribution tables.Results: Median age of the patients was 27 years and duration of INFERTILITY 2 to 15 years. 84% of patients had azospermia in seminal fluid analysis and 16% sever oligospermia. In 16 cases Bilateral TESTICULAR BIOPSY was performed in wich 18.7% of them morphological features, in testicles were different from eachother.Morphologic patterns were as follows: 15% normal spermatogensis, 30.9% sertoli cell only syndrome, 17.5% complete & incomplete maturation arrest, 14.2% tubular atrophy, 14.2% hypospermatogenesis and 8.4% mixed atrophy.Conclusion: The most and least common histopathologic pictures in testicular biopsies of the infertile men observed in this study were Germ cell aplasia and Focal tubular atrophy respectively.Diverse diseases and etiologies could be associated with any of the histopathologic pictures so that it merits a logic interpretation of these histologic changes in regard to clinical findings to specify the true cause(s) of the INFERTILITY.

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APA: Copy

KHOEI, A., & TAFAZOLI, M.. (2005). HISTOLOGIC EVALUATION OF 120 INFERTILE TESTICULAR BIOPSY. MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES, 47(86), 373-382. SID. https://sid.ir/paper/51692/en

Vancouver: Copy

KHOEI A., TAFAZOLI M.. HISTOLOGIC EVALUATION OF 120 INFERTILE TESTICULAR BIOPSY. MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2005;47(86):373-382. Available from: https://sid.ir/paper/51692/en

IEEE: Copy

A. KHOEI, and M. TAFAZOLI, “HISTOLOGIC EVALUATION OF 120 INFERTILE TESTICULAR BIOPSY,” MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES, vol. 47, no. 86, pp. 373–382, 2005, [Online]. Available: https://sid.ir/paper/51692/en

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