PREVALENCE AND PROGNOSTIC RELEVANCE OF SICK EUTHYROID SYNDROME IN INTENSIVE CARE UNIT
PATIENTS IN EMAM REZA HOSPITAL

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MOUSAVI Z.; SHARIFIPOUR FARZANEH; ASADPOOR M.A.

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Journal: Medical Journal of Mashhad University of Medical Sciences Year:2006 | Volume:49 | Issue:91 Page(s): 81-86

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Title

PREVALENCE AND PROGNOSTIC RELEVANCE OF SICK EUTHYROID SYNDROME IN INTENSIVE CARE UNIT PATIENTS IN EMAM REZA HOSPITAL

Author(s)

MOUSAVI Z. | SHARIFIPOUR FARZANEH | ASADPOOR M.A. | Issue Writer Certificate

Keywords

SICK EUTHYROID SYNDROME (SES)Q3

NON THYROIDAL ILLNESS SYNDROME (NTI)Q3

Abstract

Introduction: Altered thyroid function in patients with non-thyroidal illnesses a usuall finding and These biochemical changes called sick euthyroid syndrome (SES). Our propose from this research is to estimate the relative frequency of SES and prognostic relevance of alteration in thyroid function indices in critically ill patients whom admitted in ICD. Material and Methods: This prospective analytical study was preformed in Imam Reza Hospital intensive care unit patients.A specimen of venous blood was collected within the first. 24 hours of admission for the evaluation of the baseline thyroid function indices and second specimen was collected at the time of patient death or discharge from ICD. T4, T3 (RIA) T3 RD (RIA method), TSH (IRMA) and free T4 (Direct one step RIA) were measured for all patients.Results: There were 29 males and 21 females, with age range of 16 to 83 years and mean age of 44 years (44±21.9). Thirty three patients ( 66%) showed evidence of SES and 17 patients ( 34%) were as non SES group.Mortality rate in SES and non -SES group was 24 and 3 patient respectively (72% vs. 17.6%, P< 0.01) The commonest profile of thyroid indices was isolated low total T3 (type I SES), and then Combined low total T3 & T4.(Type II SES) We found low (T3) (type I) in 51% of patients, and low T3 and T4 (type II) in 49% of them Relative morality rate have not any difference in two groups.Comparison of mean values of thyroid indices between single system and multi system illness groups showed statistical difference in TSH (P= 0.05) and FT4. (P=0.031) Comparison of thyroid indices between two survived and non survived group showed statistical difference in T3 (p = 0.047) and T4 (P=0.036).Predictive value of normal T3 with good outcome measured 82% against 54% for normal T4. Conclusion: Relative frequency of SES in our patients was 66% and in them thyroid hormones have statistical relation with final outcome and severity of underling illness.

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APA: Copy

MOUSAVI, Z., SHARIFIPOUR, FARZANEH, & ASADPOOR, M.A.. (2006). PREVALENCE AND PROGNOSTIC RELEVANCE OF SICK EUTHYROID SYNDROME IN INTENSIVE CARE UNIT PATIENTS IN EMAM REZA HOSPITAL . MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES, 49(91), 81-86. SID. https://sid.ir/paper/51821/en

Vancouver: Copy

MOUSAVI Z., SHARIFIPOUR FARZANEH, ASADPOOR M.A.. PREVALENCE AND PROGNOSTIC RELEVANCE OF SICK EUTHYROID SYNDROME IN INTENSIVE CARE UNIT PATIENTS IN EMAM REZA HOSPITAL . MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2006;49(91):81-86. Available from: https://sid.ir/paper/51821/en

IEEE: Copy

Z. MOUSAVI, FARZANEH SHARIFIPOUR, and M.A. ASADPOOR, “PREVALENCE AND PROGNOSTIC RELEVANCE OF SICK EUTHYROID SYNDROME IN INTENSIVE CARE UNIT PATIENTS IN EMAM REZA HOSPITAL ,” MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES, vol. 49, no. 91, pp. 81–86, 2006, [Online]. Available: https://sid.ir/paper/51821/en

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