EFFECTS OF KNOTWEET OR POLYGONUM AVICULARE HERBAL EXTRACT ON PROLIFERATION OF HELA CELL LINE

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BANAZADEH HOSSEIN; DELAZAR ABBAS; HABIBI ROUDKENAR MEHRYAR; RAHMATI YAMCHI MOHAMMAD; SADEGHZADEH OSCOUI BEHNAZ; MEHDIPOUR AHMAD; SOLEIMANI RAD JAFAR; MOHAMMADI ROUSHANDEH AMANEH

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Journal: Medical Journal of Mashhad University of Medical Sciences Year:2012 | Volume:54 | Issue:4 Page(s): 238-242

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Title

EFFECTS OF KNOTWEET OR POLYGONUM AVICULARE HERBAL EXTRACT ON PROLIFERATION OF HELA CELL LINE

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Keywords

CERVICAL CANCERQ2

HELA CELL LINEQ2

POLYGONUM AVICULAREQ3

PROLIFERATIONQ2

Abstract

Introduction: CERVICAL CANCER is the most common cancer in women living in developing countries. Recently, for treatment of diseases such as cancer, herbal medicine is used as a supplementary. The Aim of this study was assessment of anticancerous effects of POLYGONUM AVICULARE herbal extract on Hela CERVICAL CANCER cell lineMaterials and Methods: HeLa cells were cultured in RPMI -1640 with 10% Fetal Bovine Serum in 5% Co2 and at 37oC in different concentrations (0, 0.005, 0.05, 0.01, 0.025, 0.075, 0.1, 0.125, 0.15, 0.175, 0.2, 0.25, 0.3, 0.35, 0.5, 5 mg/ml) of POLYGONUM AVICULARE. For assessment of viability of cells, trypan blue staining was performed. MTT assay was used for PROLIFERATION detection. Results: our results showed that in 0.15, 0.20 and 0.35 mg/ml PROLIFERATION of HeLa cells decreased according to MTT assay.Conclusion: It was proved that POLYGONUM AVICULARE had antioxidant component and could be a scavenger of free radical. Because of high production of free radicals in diseases such as cancer, the use of the herbal medicine with high amount of antioxidant could be a supplementary treatment in cancer and other diseases.

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APA: Copy

BANAZADEH, HOSSEIN, DELAZAR, ABBAS, HABIBI ROUDKENAR, MEHRYAR, RAHMATI YAMCHI, MOHAMMAD, SADEGHZADEH OSCOUI, BEHNAZ, MEHDIPOUR, AHMAD, SOLEIMANI RAD, JAFAR, & MOHAMMADI ROUSHANDEH, AMANEH. (2012). EFFECTS OF KNOTWEET OR POLYGONUM AVICULARE HERBAL EXTRACT ON PROLIFERATION OF HELA CELL LINE. MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES, 54(4), 238-242. SID. https://sid.ir/paper/51847/en

Vancouver: Copy

BANAZADEH HOSSEIN, DELAZAR ABBAS, HABIBI ROUDKENAR MEHRYAR, RAHMATI YAMCHI MOHAMMAD, SADEGHZADEH OSCOUI BEHNAZ, MEHDIPOUR AHMAD, SOLEIMANI RAD JAFAR, MOHAMMADI ROUSHANDEH AMANEH. EFFECTS OF KNOTWEET OR POLYGONUM AVICULARE HERBAL EXTRACT ON PROLIFERATION OF HELA CELL LINE. MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES[Internet]. 2012;54(4):238-242. Available from: https://sid.ir/paper/51847/en

IEEE: Copy

HOSSEIN BANAZADEH, ABBAS DELAZAR, MEHRYAR HABIBI ROUDKENAR, MOHAMMAD RAHMATI YAMCHI, BEHNAZ SADEGHZADEH OSCOUI, AHMAD MEHDIPOUR, JAFAR SOLEIMANI RAD, and AMANEH MOHAMMADI ROUSHANDEH, “EFFECTS OF KNOTWEET OR POLYGONUM AVICULARE HERBAL EXTRACT ON PROLIFERATION OF HELA CELL LINE,” MEDICAL JOURNAL OF MASHHAD UNIVERSITY OF MEDICAL SCIENCES, vol. 54, no. 4, pp. 238–242, 2012, [Online]. Available: https://sid.ir/paper/51847/en

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